Medical-grade silicone elastomers were subjected to accelerated aging in saline to verify the hydrolytic stability of the elastomer. Tensile strength, elongation at break, and the elastomer stress measured at 100% or 200% elongation did not change significantly for peroxide-cured sheeting aged in 37 degrees C or 100 degrees C saline for 45 h. Under similar condition, hydrosilylation cured sheet...

GDF11 has recently emerged as a powerful anti-aging candidate, found in young blood, capable of rejuvenating a number of aged tissues, such as heart, skeletal muscle and brain. However, recent reports have shown contradictory data questioning its capacity to reverse age-related tissue dysfunction. The availability of a mouse model of accelerated aging, which shares most of the features occurrin...

In order to evaluate the reliability of using repulped cellulose in transformers, the aging process was applied on standard and repulped cellulose in a laboratory accelerated model by increasing of temperature to 150 ° C and their behavior was monitored by measuring the amount of 2-furfural released in oil by HPLC (High Performance Liquid Chromatography) in the consecutive aging periods and...

Correlative evidence links stress, accumulation of oxidative cellular damage, and aging in several species. Genetic studies in species ranging from yeast to mammals revealed several pathways regulating stress response and life span, including caloric intake, mitochondrial respiration, insulin/IGF-1 (IIS), and JNK (c-Jun N-terminal kinase) signaling. How IIS and JNK signaling cross-talk to defen...