CONTEXT Sleep abnormalities, including obstructive sleep apnea (OSA), have been associated with insulin resistance. OBJECTIVE To determine the relationship between sleep, including OSA, and glucose parameters in a prospectively assembled cohort of chronically sleep-deprived obese subjects. DESIGN Cross-sectional evaluation of a prospective cohort study. SETTING Tertiary Referral Research ...

AIMS To investigate the associations of the apolipoprotein E phenotype (apoE) and disturbed glucose metabolism with cognitive function in a random population sample. METHODS A cross-sectional study was conducted, in which 528 men aged 54 or 60 years were recruited randomly from a larger population-based sample of 1516 men. A subject was defined as having abnormal glucose tolerance (AGT), if h...

BACKGROUND Polycystic ovary syndrome (PCOS) is associated with metabolic disturbances which include impaired insulin signalling and glucose metabolism in ovarian follicles. The oocyte is metabolically dependent upon its follicle environment during development, but it is unclear whether PCOS or polycystic ovarian (PCO) morphology alone affect oocyte metabolism and energy-demanding processes such...

BACKGROUND The aim of this meta-analysis was to explore the correlations of abnormal glucose metabolism (AGM) with bone mineral density (BMD) and bone metabolism. MATERIAL/METHODS Relevant studies were identified using computerized and manual search strategies. The included studies were in strict accordance with inclusion and exclusion criteria. Statistical analyses were conducted with the Co...

Recent studies indicate an important role of the kidney in postprandial glucose homeostasis in normal humans. To determine its role in the abnormal postprandial glucose metabolism in type 2 diabetes mellitus (T2DM), we used a combination of the dual-isotope technique and net balance measurements across kidney and skeletal muscle in 10 subjects with T2DM and 10 age-, weight-, and sex-matched non...

background & aim: diabetes mellitus often has been referred to as a syndrome of disordered metabolism, usually due to a combination of hereditary and environmental causes, resulting in abnormal of high blood sugar levels (hyperglycemia). nowadays, no-drug treatments (medicinal plants) are novel therapeutic approaches in the treatment of diabetes. experimental: this study aimed at assessing ...

Abstract Objective: The aim of this study was evaluating the relationship between maternal serum lipid measured at 13-23 weeks of pregnancy and subsequent glucose intolerance. Materials and Methods: In a prospective study, 624 pregnant women prior to 23 weeks were eligible for the study. Primarily, serum levels of total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride were ...