Moderately priced oscilloscopes available for the NIF power sensors and target diagnostics have 6 GHz bandwidths at 20-25 Gsamples/s (40 ps sample spacing). Some NIF experiments require cross timing between instruments be determined with accuracy better than 30 ps. A simple analysis algorithm for Gaussian-like pulses such as the 100-ps-wide NIF timing fiducial can achieve single-event cross-tim...

Background: Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6C and patrolling Ly6C monocytes. Alarmins S100A8/A9 locally released by the synovium during inflammatory OA for prolonged periods may be dominant proteins involved in stimulating recruitment of Ly6C monoc...

BACKGROUND Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6Chigh and patrolling Ly6Clow monocytes. Alarmins S100A8/A9 locally released by the synovium during inflammatory OA for prolonged periods may be dominant proteins involved in stimulating recruitment of Ly6C...

The present study aimed to elucidate the role of cluster of differentiation (CD)8+, CD4+, natural killer (NK), and myeloid (CD11b+) cells in the course of the growth and rejection of experimental major histocompatibility complex (MHC) class I-deficient, HPV16 E6/E7-associated TC-1/A9 tumors in mice. Stable mouse lines (F30) generated by inbreeding of Balb/c and C57BL/6 strains, which were chara...

The introduction of commercially available in vitro diagnostic (IVD) PCR assays into the clinical microbiology laboratory has facilitated enhancements to patient care, improving diagnostic sensitivity and specificity (1–3). Recently, PCR assays for the detection of the Clostridium difficile toxin B gene have become available. A number of these commercial assays require little or no special expe...

Neuroinflammation is a hallmark of Amyotrophic Lateral Sclerosis (ALS) in hSOD1G93A mouse models where microglial cells contribute to the progressive motor neuron degenerative process. S100-A8 and S100-A9 (also known as MRP8 MRP14, respectively) are cytoplasmic proteins expressed by inflammatory myeloid cells, including microglia macrophages. Mainly acting heterodimer, S100-A8/A9, when secreted...

background: the biolimus-eluting stent (bes), with a biodegradable polymer, has not been previously compared with the everolimus-eluting stent (ees), as a second-generation drug-eluting stent (des).we sought to compare the 1-year outcome between the promus ™ stent (ees type) and the biomatrix ™ stent (bes type). methods: from march 2008 to september 2011, all patients treated with the promus™ s...

For thousands of years engineers have dreamed of building machines with vision capabilities that match their own. However most image processing algorithms are computationally intensive making real-time implementation di cult, expensive and not usually possible with microprocessor based hardware. In this project a computationally intensive image-processing algorithm is implemented, analysed, and...

Mouse A9 cells containing human chromosome 7 tagged with pSV2neo were irradiated with X-rays and fused to A9 cells to isolate G418-resistant clones. From these clones, we selected radiation hybrids that contained 10-40 Mb of human DNA apparently at a single site of their genome by FISH analysis using human repetitive sequences as a probe. Then we made a panel of hybrids that contained various f...