ADAMTS13 specifically cleaves plasma von Willebrand factor (VWF) and thereby controls VWF-mediated platelet thrombus formation. Severe deficiencies in ADAMTS13 can cause life-threatening thrombotic thrombocytopenic purpura. Here, we determined 2 crystal structures of ADAMTS13-DTCS (residues 287-685), an exosite-containing human ADAMTS13 fragment, at 2.6-A and 2.8-A resolution. The structures re...

Large pellicle fragments were isolated from Tetrahymena pyriformis, strain T, by 2 procedures : homogenization after treatment with 40 % ethanol at — 20 °C, or direct homogenization in a sucrose-EDTA buffer. All preparations contained entrapped mitochondria. DNA prepared from these pellicles was analysed on a CsCl gradient, and contained 3 components of buoyant densities 1-685, 1-688, and 1698 ...

A comparative study on the effect of excess copper (Cu) supplied through leaves and root treatments in soybean plants is presented. Although Cu was accumulated in leaves upon both treatments, important differences were observed between Cu treatment of leaves and Cu supplementation in hydroponic medium. The application of 50 μM CuSO4 on leaves increased chlorophyll content, oxygen evolution acti...

Aberration [828]. Aborigine [1221]. Abortion [1775]. Absolute [1956, 1764]. Acceleration [411]. Accelerator [360, 1284]. Accelerators [1727]. Acetabularia [1354]. Acid [578, 1200]. Acids [740, 855]. Acoustic [1023]. Acoustical [1924]. Acoustics [759]. ACTH [685]. Action [447]. Activation [1433]. Acute [1938]. Adaptations [1190]. Add [1731]. Addiction [823]. Adhesives [447]. Adjustable [1618]. A...

685. Factors Associated With Inter-Hospital Variability of Inpatient Antibiotic Use in a Cohort of US Hospitals James Baggs, PhD; Scott Fridkin, MD, FIDSA; Lori Pollack, MD, MPH; Arjun Srinivasan, MD, FSHEA; John Jernigan, MD, MS; Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia; Division of Healthcare Quality Promotion (DHQP), Centers for D...

y Available control technologies and strategies include direct PM2.5 reduction technologies such as fabric filters (baghouses), electrostatic precipitators (ESPs), and diesel particulate filters (DPFs). Once installed, these strategies range in cost-effectiveness from as little as $48/ton PM2.5 to $685/ton PM2.5 (2010$) or more, depending on the source category. However, they also may involve t...

Enzymes in Dried Blood Spots: Application to Newborn Screening for Krabbe Disease, Yijun Li, Knut Brockmann, Frantisek Turecek, C. Ronald Scott, and Michael H. Gelb (Departments of 1 Chemistry, 3 Pediatrics, and 4 Biochemistry, University of Washington, Seattle, WA; 2 Department of Pediatrics and Neuropediatrics, Children’s Hospital, University of Goettingen, Goettingen, Germany; * address corr...