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Introduction: Clinical application of platinum-based anticancer drugs is largely limited by severe toxicity. Drug delivery systems are highly desired for improving the efficacy and applicability of these drugs. This study describes an alternative strategy for the delivery of a new synthesized Pt(II) complex (bipyridin morpholin dithio carbomate Pt(II) nitrate) by its encapsulating in the Beta-C...

1,3-benzodioxle-4-carboxylic acid] was designed as a novel class of chiral fluorometric agents.1 The chiral agent and the analogues have been conveniently applied to enantiomer analyses of various bio-molecules using HPLC and circular dichroism.2 We recently extended the molecular design of (S)TBMB carboxylic acid to chiral nitrobenzoic acids possessing the asymmetric 1,3-benzodioxole.3 The chi...

In this paper, based on the 3-dimensional discrete cosine transform(DCT) for removing the temporal correlation, an adaptive 3-D transform coding technique is proposed. Because of the nonstationary nature of the image data, the energy distribution in a 3-D DCT block varies along the vertical, horizontal and temporal directions. Thus, adaptive schemes, such as the 3-D classi cation, the classi ed...

Biological radiation effects are usually estimated by epidemiological data, while the statistical effectiveness of epidemiological analysis for low dose radiation is limited. This is the reason why cellular and molecular biology data have also been employed to estimate radiation effects. However, the relationship of the adverse effects at the human scale with microscopic phenomena has rarely be...

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Background Adult-onset Still’s disease (AOSD) and Systemic Juvenile Idiopathic Arthritis (SJIA, formerly termed Disease), are rare polygenic autoinflammatory disorders of unknown etiology. The clinical course AOSD/SJIA has been distinguished into different phenotypes, described on the basis evolution symptoms over time. In a sizeable proportion affected patients, remission can be achieved with ...