Article type: Original Article Introduction: The ultimate goal of radiation treatment planning is to yield a high tumor control probability (TCP) with a low normal tissue complication probability (NTCP). Historically dose volume histogram (DVH) with only volumetric dose distribution was utilized as a popular tool for plan evaluation hence present study aimed to compare the radiobiological effec...

The EBT-XD model of Gafchromic™ films has a broader optimal dynamic dose range, up to 40 Gy, compared with its predecessor models. This characteristic made suitable for high-dose applications, such as stereotactic body radiotherapy and radiosurgery, well ultra-high rate FLASH radiotherapy. purpose the current study was characterize dependence film response on linear energy transfer (LET) therap...

Introduction: Siliconeprosthetic implants are commonlyutilizedfor tissue replacement and breast augmentation after mastectomy. On the other hand, some patients require adjuvant radiotherapy in order to preventlocal-regional recurrence and increment ofthe overall survival. In case of recurrence, the radiation oncologist might have to irradiate the prosthesis.The aim of this study was to evaluate...

Introduction: Radiation therapy following breast conserving surgery is one of the most common procedures performed in any radiation oncology department. A tangential parallel-opposed pair is almost always the technique of choice for this purpose. This technique is often performed based on 3D treatment planning. The aim of this study was to compare 3D treatment planning for two different energie...

Our study is considered a continuing effort in radiation therapy treatment of breast cancer. It is concerned a comparison study between the effect of hyperfractionation radiotherapy (a short term course) and hypofractionation radiotherapy (a long term course) of treatment photon doses on breast cancer cells. The comparison is done with refereeing to normal breast tissue measurements using flow ...

Introduction: The aim of the present study was to assess the radiosensitivity parameters for SK-BR-3 (SKBR3) breast cancer cells that could be implemented in the cutting-edge treatment planning systems (TPS) for accelerated partial-breast irradiation (APBI). Materials and Methods: The cell survival fraction and its relevant radiosensitivity coefficients, namely α and β, in linear-quadratic (LQ)...

OBJECT The authors sought to assess the safety and efficacy of stereotactic radiotherapy when using a linear accelerator equipped with a micromultileaf collimator for the treatment of patients with acoustic neuromas. METHODS Fifty patients harboring acoustic neuromas were treated with stereotactic radiotherapy between September 1997 and June 2003. Two patients were lost to follow-up review. P...

OBJECTIVE To determine whether teletherapy with 6-mV photons can reduce visual loss in patients with subfoveal choroidal neovascularization in age-related macular degeneration. DESIGN A multicenter, single-masked, randomized controlled trial of 12 Gy of external beam radiation therapy delivered to the macula of an affected eye vs observation only. SETTING Three United Kingdom-based hospital...

Unlike scheduled radiotherapy treatments, treatment planning time and resources are limited for emergency treatments. Consequently, plans are often simple 2D image-based treatments that lag behind technical capabilities available for nonurgent radiotherapy. We have developed a novel integrated urgent workflow that uses onboard MV CBCT imaging for patient simulation to improve planning accuracy ...

Study has been made of the thermoluminescence (TL) response of silica-based Ge-doped cylindrical, flat and photonic crystal fibres (referred to herein as PCF-collapsed) to electron (6, 12 and 20 MeV) and photon (6, 10 MV) irradiation and 1.25 MeV γ-rays, for doses from 0.1 Gy to 100 Gy. The electron and photon irradiations were delivered through use of a Varian Model 2100C linear accelerator lo...