نتایج جستجو برای: 5 فلورویوراسیل

تعداد نتایج: 1215768  

Journal: :Nucleic acids research 2004
Archna P Massey Snorri Th Sigurdsson

The chemical syntheses of RNA oligomers containing modifications on the 5'-carbon of the 5'-terminal nucleoside for crystallographic and mechanistic studies of the hairpin ribozyme are reported. Phosphoramidites 4 and 8 were prepared and used in solid phase syntheses of RNA oligomers containing the sequence 5'-N'UCCUCUCC, where N' indicates either 5'-chloro-5'-deoxyguanosine or 5'-amino-5'-deox...

2012
Marty Hinz Alvin Stein Thomas Uncini

L-5-hydroxytryptophan (5-HTP) is the immediate precursor of serotonin. It is readily synthesized into serotonin without biochemical feedback. This nutrient has a large and strong following who advocate exaggerated and inaccurate claims relating to its effectiveness in the treatment of depression and a number of other serotonin-related diseases. These assertions are not supported by the science....

2011
Aleksandra Szwagierczak Andreas Brachmann Christine S. Schmidt Sebastian Bultmann Heinrich Leonhardt Fabio Spada

In mammalian genomes a sixth base, 5-hydroxymethylcytosine ((hm)C), is generated by enzymatic oxidation of 5-methylcytosine ((m)C). This discovery has raised fundamental questions about the functional relevance of (hm)C in mammalian genomes. Due to their very similar chemical structure, discrimination of the rare (hm)C against the far more abundant (m)C is technically challenging and to date no...

Journal: :Chemical communications 2011
Akiko Nomura Kaori Sugizaki Hiroyuki Yanagisawa Akimitsu Okamoto

An artificial phosphopeptide recognized the difference between methylated and hydroxymethylated cytosines in DNA. The Sp1 zinc finger peptide substituted by phosphotyrosine effectively discriminated between 5-methylcytosine, 5-hydroxymethylcytosine ((hm)C) and unmethylated cytosine. The DNA recognition properties of the peptide differ from those of other chemicals that detect (hm)C.

Journal: :Bulletin of the Chemical Society of Japan 1983

Journal: :Microbiology and Immunology 1991

Journal: :ACS Chemical Neuroscience 2014

Journal: :Journal of Optical Communications 2015

2013
G. Klimke R. Mengel M. J. Robins

Adenosine Analogs, Conformation, NMR The solution conformation of adenosine(/Oribosides modified at the 2', 3' or 5' position is derived from the analysis o f the HRNM R spectra of the ribose protons. The conformational equilibria of the furanoside rings are described by the two state N <-+ S model introduced by Altona and Sundaralingam. The new compounds studied are: 2'-thiobenzoyl-2'-deoxyade...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید