نتایج جستجو برای: 5α dihydrotestosterone
تعداد نتایج: 3573 فیلتر نتایج به سال:
Inhibition of 5α-reductase (5αR), which blocks the conversion testosterone to its active metabolite, dihydrotestosterone, has been shown impact further prostate enlargement (benign prostatic hyperplasia, or BPH). Clinical trials standardized lipidosterolic extracts Serenoa repens (LSESr), also known as saw palmetto, have demonstrated improvement in lower urinary tract symptoms (LUTS) and delaye...
Benign prostatic hyperplasia (BPH) is the most common condition in aging men, associated with lower urinary tract symptoms. It is caused due to the augmented levels of the androgen dihydrotestosterone. Dutasteride, a 5α-Reductase inhibitor has been recommended for the treatment of BPH upon oral administration. However, long term oral administration of dutasteride may cause sexual problem in man...
CONTEXT Steroid 5α-reductase inhibitors are used to treat benign prostatic hyperplasia and androgenic alopecia, but the role of 5α-dihydrotestosterone (DHT) in mediating testosterone's effects on muscle, sexual function, erythropoiesis, and other androgen-dependent processes remains poorly understood. OBJECTIVE To determine whether testosterone's effects on muscle mass, strength, sexual funct...
The metabolism of progesterone bound to uterine nuclear progesterone receptors was accelerated in vitro by incubation at 25°C for 30min with NADPH generator. The characteristics of progesterone metabolites and receptors were examined by 3H-R5020 exchange assay. Progesterone bound nuclei were prepared from uteri of estradiol-primed progesteronetreated ovariectomized rats. The specific nuclear R5...
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