Champion, Hunter C., Trinity J. Bivalacqua, David G. Lambert, Rasheed A. Abassi, and Philip J. Kadowitz. Analysis of vasoconstrictor responses to histamine in the hindlimb vascular bed of the rabbit. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1179–R1187, 1999.—Hemodynamic responses to histamine were investigated in the anesthetized rabbit. Intravenous injections of histami...

Hughes, Jeremy, and Richard J. Johnson. Role of Fas (CD95) in tubulointerstitial disease induced by unilateral ureteric obstruction. Am. J. Physiol. 277 (Renal Physiol. 46): F26–F32, 1999.—Murine renal tubular epithelial cells and interstitial fibroblasts may express both Fas (CD95) death receptor and Fas ligand and are vulnerable to Fas-mediated death in vitro. We therefore hypothesized that a...

Shirasaka, Tetsuro, Masamitsu Nakazato, Shigeru Matsukura, Mayumi Takasaki, and Hiroshi Kannan. Sympathetic and cardiovascular actions of orexins in conscious rats. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1780–R1785, 1999.—The novel hypothalamic peptides orexin-A and orexin-B are known to induce feeding behavior when administered intracerebroventricularly, but little is...

Butler, Karyn L., Alice H. Huang, and Judith K. Gwathmey. AT1-receptor blockade enhances ischemic preconditioning in hypertrophied rat myocardium. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H2482–H2487, 1999.—The purpose of this study was to determine whether ischemic preconditioning protects contractile function in hypertrophied rat myocardium from ischemia-reperfusion (I/R) injury. Male s...

Arai, Andrew E., Claudia E. Kasserra, Paul R. Territo, Amir H. Gandjbakhche, and Robert S. Balaban. Myocardial oxygenation in vivo: optical spectroscopy of cytoplasmic myoglobin and mitochondrial cytochromes. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H683–H697, 1999.— The oxygenation state of myoglobin and the redox state of cytochrome c provide information on the PO2 in the cytosol and mi...

Takito, Jiro, Lunbiao Yan, Jian Ma, Chinami Hikita, S. Vijayakumar, D. Warburton, and Qais Al-Awqati. Hensin, the polarity reversal protein, is encoded by DMBT1, a gene frequently deleted in malignant gliomas. Am. J. Physiol. 277 (Renal Physiol. 46): F277–F289, 1999.—The band 3 anion exchanger is located in the apical membrane of a b-intercalated clonal cell line, whereas the vacuolar H1ATPase ...

Itoh, Hiroaki, Jing Zheng, Ian M. Bird, Kazuwa Nakao, and Ronald R. Magness. Basic FGF decreases clearance receptor of natriuretic peptides in fetoplacental artery endothelium. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R541–R547, 1999.—Atrial natriuretic peptide (ANP) is present in the fetoplacental circulation of humans and sheep. The ANP-A receptor is the specific membra...

MICHAEL KJÆR,1 BIRGITTE HANEL,2 LARS WORM,2 GRAZYNA PERKO,2 STEVEN F. LEWIS,2 KENT SAHLIN,2 HENRIK GALBO,3 AND NIELS H. SECHER2 2Department of Anesthesia, Copenhagen Muscle Research Center, Rigshospitalet University Hospital; 3Department of Medical Physiology, Panum Institute; and 1Sports Medicine Research Unit, Department of Rheumatology H, Bispebjerg Hospital, University of Copenhagen, DK-240...

Hassid, Aviv, Shile Huang, and Jian Yao. Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins. Am. J. Physiol. 277 (Heart Circ. Physiol. 46): H192–H198, 1999.—Recent studies have focused attention on the role of protein tyrosine kinases in vascular smooth muscle cell biology, but similar information regarding protein tyrosine phosphatases ...

Bahar, Sonya, Christopher T. Gunter, Cheryl Wu, Scott D. Kennedy, and Philip A. Knauf. Persistence of external chloride and DIDS binding after chemical modification of Glu-681 in human band 3. Am. J. Physiol. 277 (Cell Physiol. 46): C791–C799, 1999.—Although its primary function is monovalent anion exchange, the band 3 protein also cotransports divalent anions together with protons at low pH. T...