ITE JOURNAL / FEBRUARY 2002 TOLL FACILITIES CANNOT BE CLASsified under the same pretenses as normal freeway segments or signalized intersections because of the unique characteristics associated with toll plazas being integrated within the system. Therefore, it is difficult to examine the operational conditions and accurately report the benefits of toll facilities to the public in terms they can...

Volume 30, Number 1, January/February 1998 swers into a laptop computer. A revised questionnaire using CAPI was pretested between October and December 1993. About 800 eligible women were selected, and 500 were interviewed. The pretest was an experiment, which compared results for women who received incentives with results for women who did not. Incentives increased response rates, reduced costs...

TAR DNA-binding protein (TDP-43) is a highly conserved and essential DNA- and RNA-binding protein that controls gene expression through RNA processing, in particular, regulation of splicing. Intracellular aggregation of TDP-43 is a hallmark of amyotrophic lateral sclerosis and ubiquitin-positive frontotemporal lobar degeneration. This TDP-43 pathology is also present in other types of neurodege...

ABSTRACT Mislocalization of the TAR DNA-binding protein 43 (TDP-43; encoded by TARDBP) from nucleus to cytoplasm is a common feature neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The downstream in vivo cellular effects this mislocalization are not well understood. To investigate impact mislocalized TDP-43 on neuronal cell ...

Introduction Many educational practitioners in the United Kingdom, working with the challenge of a diverse learning population, provide simplified language materials (SLMs) to their students (Barnard & Burgess, 2001; Rix, 2004, 2006). Their use in mainstream classrooms has not been evaluated however. This paper explores the manner in which teachers and support staff develop these SLMs. It repor...

Connexins proteins associate with a variety of catalytic and non-catalytic molecules. Also, different domains of connexin can bind to each other, providing a mechanism for channel regulation. Here, we review some of these associations, placing particular emphasis on the intramolecular interactions that regulate Connexin43 (Cx43). We also describe some novel methods that allow for the characteri...