نتایج جستجو برای: 4 thiazolidinediones

تعداد نتایج: 1304987  

Journal: :Endocrinology 2005
A M Schwab S Granholm E Persson B Wilkes U H Lerner H H Conaway

Dosage-dependent release of 45Ca was observed from prelabeled mouse calvarial bones after treatment with two thiazolidinediones, troglitazone and ciglitazone. Release of 45Ca by ciglitazone was decreased by the osteoclast inhibitors acetazolamide, calcitonin, 3-amino-1-hydroxypropylidene-1,1-bisphosphonate, and IL-4, but not affected by the peroxisome proliferator-activated receptor gamma antag...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2005
Anna C Calkin Josephine M Forbes Craig M Smith Markus Lassila Mark E Cooper Karin A Jandeleit-Dahm Terri J Allen

OBJECTIVE Recent studies have demonstrated a role for thiazolidinediones in attenuating atherosclerosis. However, these studies were performed in insulin-resistant animal models in association with reductions in insulin and glucose levels. To assess the vascular effects of thiazolidinediones, independent of their metabolic effects, we observed the effect of rosiglitazone on diabetes-associated ...

Journal: :Circulation 2003
Nikolaus Marx Armin Imhof Johannes Froehlich Laila Siam Jochen Ittner Gerhard Wierse Arnold Schmidt Winfried Maerz Vinzenz Hombach Wolfgang Koenig

BACKGROUND Interaction of CD40L with its receptor CD40 is critically involved in inflammatory cell activation in atherogenesis. In addition, serum levels of soluble CD40L are elevated in acute coronary syndromes and have been associated with increased cardiovascular risk in healthy subjects, thus making sCD40L an intriguing target to modulate the inflammatory response in the vasculature. PPARga...

2015
Shusuke Yagi Ken-ichi Aihara Masataka Sata

Corresponding author: Shusuke Yagi Department of Cardiovascular Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan E-mail: [email protected] We appreciate Dr. Ye An Kim’s comments on our study entitled “Predictive factors for efficacy of dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes mellitu...

Journal: :Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2012
K Celinski T Dworzanski R Fornal A Korolczuk A Madro M Slomka

Non-specific inflammatory bowel diseases, including ulcerative colitis and Crohn`s disease, are chronic non-infectious diseases that showed an increase in prevalence in recent years, particularly in the developed countries. The effective methods of their treatment and prevention of recurrences are currently under investigation. One type of therapy that can prevent the inflammatory recurrence in...

Journal: :The Journal of Clinical Endocrinology & Metabolism 2009

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