نتایج جستجو برای: 4 and il

تعداد نتایج: 17047826  

Background : Allergic asthma is a chronic inflammatory disease of airway that often determined with degrees of inflammation, hypersensitivity, bronchial constriction and airway changes. Th1, Th2 and Th17 cells are the main cells involved in the pathophysiology of asthma. . Therefore, this study evaluated Th1, Th2, and Th17 cells functions by assessment the expression of INF-g, IL-4, and IL-17 g...

Pemphigus vulgaris (PV) is a chronic autoimmune blistering disease of the skin, in whichloss of adhesion between keratinocytes is caused by autoantibodies. It has been hypothesizedthat cytokines play an essential role in the pathogenesis of PV. This study aimed to investigatethe other immunopathological aspects of PV by determining the serum levels of cytokines inPV patients to find another tre...

Journal: :Journal of immunology 2003
Richard T Strait Suzanne C Morris Kristi Smiley Joseph F Urban Fred D Finkelman

We evaluated whether IL-4, a cytokine critical for inducing allergic responses, also contributes to the effector phase of allergy. Pretreatment of mice with IL-4 or the related cytokine, IL-13, rapidly and dramatically increased the severity of anaphylaxis induced by cross-linking Fc(epsilon)RI or FcgammaRIII. This effect was inhibited by endogenously produced IFN-gamma, was T cell-, B cell-, a...

Journal: :International Journal of Molecular Sciences 2021

Journal: :archives of pediatric infectious diseases 0
azar nickavar pediatric nephrology department, aliasghar children’s hospital, iran university medical sciences, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (iran university of medical sciences) baranak safaeian division of pediatric nephrology, neonatal and children’s health research center, golestan university of medical sciences, gorgan, iran; division of pediatric nephrology, neonatal and children’s health research center, golestan university of medical sciences, gorgan, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی گلستان (golestan university of medical sciences) ehsan valavi division of nephrology, pediatric department, abuzar children’s hospital, ahvaz university medical sciences, ahvaz, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی جندی شاپور اهواز (ahvaz jundishapur university of medical sciences)

results mean urinary il-1α, il-4, il-6, and il-8 concentrations significantly increased in the acute phase of apn compared to the control group, and decreased following antibiotic treatment. conclusions we recommend routine urinalysis and urine culture for the diagnosis of children with apn. urinary il-4 was a relatively good cytokine for the prediction and treatment-monitoring of children with...

Objective(s): Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are regarded as autoimmune diseases of the central nervous system (CNS).  The CNS, testes, and eyes are immune privileged sites.  It was initially presumed that ocular involvement in EAE and infertility in MS are neural-mediated.  However, inflammatory molecules...

Journal: :American Journal of Respiratory and Critical Care Medicine 2015

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