Cryopreservation and transplantation of ovarian tissue (OT) represents a method for fertility preservation. However, as the transplantation is performed without vessel anastomosis, unavoidable ischemic damage occurs. To reduce this ischemic damage and improve outcomes after transplantation, we used two kind of angiogenic factors, angiopoietin-2 (ang-2) and vascular endothelial growth factor (VE...

BACKGROUND.: We have shown that high-dose intravenous immune globulin (IVIG; 2 g/kg x2 doses)+rituximab (1 g x2 doses) was effective in lowering anti-human leukocyte antigen (HLA) antibodies and improving rates of transplantation. The aim of this report was to evaluate the efficacy of IVIG+rituximab on reduction of anti-HLA antibodies to a level that was permissive for living donor (LD) or dece...

The current study examined the contributions of angiotensin-converting enzyme (ACE) vs. chymase to angiotensin II (ANG II) generation in membrane preparations from left ventricles of humans, dogs, rabbits, and rats and from total heart of mice. ACE and chymase activity were measured in membrane preparations extracted with low or high detergent (LD and HD, respectively) concentrations. We hypoth...

oral contraceptive pills have several side effects especially on the gastrointestinal tract and liver. absorption of low dose (ld) pills by the vaginal route avoids the first pass of the steroids through these tracts and probably has fewer side effects. this study was a cohort study for evaluation of side effects and acceptability of ld pills administered by the vaginal route. in a clinical tri...

For the classical gradient method xt+1 = xt − γt∇f(xt) and several deterministic and stochastic variants, we discuss the issue of convergence of the gradient sequence ∇f(xt) and the attendant issue of stationarity of limit points of xt. We assume that ∇f is Lipschitz continuous, and that the stepsize γt diminishes to 0 and satisfies standard stochastic approximation conditions. We show that eit...

Using the method of transportation-information inequality introduced in [28], we establish Bernstein type’s concentration inequalities for empirical means 1 t ∫ t 0 g(Xs)ds where g is a unbounded observable of the symmetric Markov process (Xt). Three approaches are proposed : functional inequalities approach ; Lyapunov function method ; and an approach through the Lipschitzian norm of the solut...

With the advent of field-effect transistor (FET) technology it has become practical and economical to employ complex functions as network primitives. This paper describes a synthesis procedure for diagnosable (all single and multiple faults can be detected) FET networks. A companion procedure for generating tests to detect all faults in the resulting network is also described. This methodology ...