Mouse (m) and human embryonic stem cell-derived cardiomyocytes (hESC-CMs) are known to exhibit immature Ca(2+) dynamics such as small whole-cell peak amplitude and slower kinetics relative to those of adult. In this study, we examined the maturity and efficiency of Ca(2+)-induced Ca(2+) release in m and hESC-CMs, the presence of transverse (t) tubules and its effects on the regional Ca(2+) dyna...

Laminin-332 (LM-332, formerly termed laminin-5) is a heterotrimeric glycoprotein that regulates cell adhesion and migration. Molecular alterations of LM-332 are involved in cancer progression. The aim of this study was to clarify alterations of LM-332 in gastric carcinoma. The expression of LM-332 subunits in 10 gastric carcinoma cell lines was investigated by RT-PCR, Western blotting, and immu...

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau...

STUDY OBJECTIVE During dengue epidemics, emergency physicians face large numbers of patients with acute febrile illness. Triage algorithms and appropriate reporting systems are useful to manage patients and prioritize resources. We identify possible adaptations to these systems to improve the management of patients during epidemics. METHODS In a prospective observational study in the adult em...

Lysophosphatidic acid (LPA) is a bioactive phospholipid that affects various biological functions, such as cell proliferation, migration, survival, wound healing, and tumor invasion through LPA receptors. Previously, we reported that LPA induces A431 colony dispersal, accompanied by disruption of cell-cell contacts and cell migration. However, it remains unclear how LPA affects cell migration a...

Ressenya a Josep Lluís Martos: El primer cancionero impreso y un pliego poético incunable, Madrid-Frankfurt: Iberoamericana -Vervuert, 2023, 332 pp. ISBN: 978-84-9192-332-9 Review to

This paper explores the role of unionization on the wages of Hispanic workers in the US from 1994 to 2013. Preliminary evidence indicates a 25 to 29 percent positive wage gap between unionized Hispanic male workers and their non-unionized counterparts. Once we control for socio-demographic characteristics and account for non-random selection into union membership, there is still a positive effe...

The Model-Driven Engineering paradigm has become increasingly popular due to its advocation of using models as first-class citizens in the software development process, while artifacts such as documentation and source-code can be produced from those models by using automated transformations. On the other hand, we are currently witnessing the rise in popularity of a particular kind of web-applic...

The effect of external as well as internal bremsstrahlung radiation in H ! ZZ ! 4e channel is studied in full detector simulation. A method is proposed for external and internal bremsstrahlung recovery, allowing us to use 95% of electrons within j E=pgen 1 j 0.2. It is shown that traditional E=p and isolation cuts can be implemented with 90% efficiency, but that precise mass reconstruction is a...

Suspensions of fat cells were prepared from rat epididymal adipose tissue by digestion of the tissue with crude bacterial collagenase. One portion of each suspension was exposed to p-chloromercuribenzenesulfonic acid (CMS), washed, and then incubated in Krebs-Ringer-bicarbonate buffer. A second portion, the control, was not exposed to CMS, but it was otherwise treated identically. Acceleration ...