Physiological processes such as ovarian follicle atresia generate large amounts of unnecessary cells or tissue detritus, which needs to be disposed of rapidly. IL-33 is a member of the IL-1 cytokine gene family. Constitutive expression of IL-33 in a wide range of tissues has hinted at its role beyond immune defense. We have previously reported a close correlation between IL-33 expression patter...

This case report presents the performance of an athlete who completed for the first time in history the total distance of 33 Ironman triathlons within 33 consecutive days. The athlete finished the total distance of 7,458 km (i.e. 125 km swimming, 5,940 km cycling and 1,393 km running) within a total time of 410 h and a mean time of 12 h 27 min per Ironman distance. During the 33 days, the athle...

IMPORTANCE Brain injury affects neurologic function and quality of life in survivors after cardiac arrest. OBJECTIVE To compare the effects of 2 target temperature regimens on long-term cognitive function and quality of life after cardiac arrest. DESIGN, SETTING, AND PARTICIPANTS In this multicenter, international, parallel group, assessor-masked randomized clinical trial performed from Nov...

The cytokine network controlling basophils has been extended to interleukin-33. This commentary provides an update and summary on this emerging concept.

The Largemouth Bass Micropterus salmoides, a popular sport fish, is subjected to multiple sublethal stressors during angling, including high water temperature, exercise, handling, live-well retention, and weigh-in procedures. Combined effects of ambient temperatures on the stress response recovery from angling-induced exercise have not been tested in conditions similar those encountered tournam...