The cDNA of the mineralocorticoid receptor (MR) was cloned 30 years ago, in 1987. At that time, spirolactone, the first generation of synthetic steroid-based MR antagonists (MRAs), which was identified in preclinical in vivo models, had already been in clinical use for 30 years. Subsequent decades of research and development by Searle & Co., Ciba-Geigy, Roussel Uclaf and Schering AG toward iden...

To evaluate the association of chlorophenol exposure with soft tissue sarcoma risk independent of phenoxyherbicide exposure, the authors analyzed data from the Selected Cancers Study, a population-based case-control study that included 295 male soft tissue sarcoma cases, aged 32-60 years, from eight population-based cancer registries and 1,908 male controls. Chlorophenol exposure was assigned u...

mihan is a new bread wheat cultivar originated from the cross between iranian cultivar barakat with the chinese cultivar 90-zhong 87 at karaj research station in 1995-96 cropping season. the f1 plants were grown at karaj in 1996-97 cropping season, furthermore f2-f6 populations and regional preliminary yield nursery were evaluated at ardebil agricultural research station during 1997-2003 croppi...

A field experiment was conducted on the Effect of phosphorus fertilizer and seed rates growth yield common bean (Phaseolus vulgaris L) at Farm agriculture faculty Kunduz University during spring season 2023 to determine optimum for maximum in northeast Afghanistan (Kunduz province). The treatment consists three levels (0kgP2O5ha-1, 40kgP2O5ha-1 80kgP2O5ha-1) four combined (125 kgha-1, 150 175 k...

background: this study was performed to effects of garlic and lemon juice mixture on lipid profile and some cardiovascular risk factors in people 30–60 years old with moderate hyperlipidemia. methods: in a parallel‑designed randomized controlled clinical trial, a total of 112 hyperlipidemic patients 30–60 years, were recruited from isfahan cardiovascular research center. people were selected an...