A series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (C1-C7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. All the synthesis compounds have been characterized by 1HNMR, IR and Mass spectral data. The compounds were purified...

The title compound, C(2)H(8)N(+)·C(6)H(4)NO(3) (-)·C(6)H(5)NO(3), was synthesized from dimethyl-amine and 4-nitro-phenol in an overall yield of 85%. The dihdral angles between the nphenyl rings and their attached nitro groups are 5.7 (6) and 2.5 (7)°. In the crystal, there are strong hydrogen bonds between the ammonium group and the nitro-phenol and nitro-phenolate O atoms, and between the nitr...

Two novel potentially bioactive compounds, esters 2-methyl-1-phenylpyridine-4-one-3-yl adamantan-1-ylethanoate (1) and 1-(p-methoxyphenyl)-2-methylpyridine-4-one-3-yl adamantan-1ylethanoate (2), were synthesized by esterification of adamantan-1-ylacetic acid with appropriate N-aryl substituted 3-hydroxypyridine-4-one derivatives. Both compounds are fully characterized using standard spectroscop...

To develop a π-conjugation circuit switched by redox reaction between 3-pyridone and 3-hydroxypyridine, ring-contracted analogue of oxypyriporphyrin, 2-oxypyritriphyrin(1.2.1) was prepared. When 2-oxypyritriphyrin treated with NaBH4, not only the 3-oxypyridine unit, but also meso-carbon reduced. The reduced analog could be oxidized again to afford in reversible manner.

Abstract Resolving the regioselectivity of N-position on nitrogen-rich heterocycles is an important task in synthesis high energy density materials (HEDMs). In this work we developed a simple two-step route to introduce 1,2,4-triazole into 4-nitro-1,2,3-triazole N2-position, which shows excellent regioselectivity. The target compound 4-nitro-2-(1 H -1,2,4-triazol-3-yl)-1,2,3-triazole (3) was ch...