to evaluate the effects of sowing date, cultivars and herbicides on weed species control and soybean yield, a strip split plot layout in as a randomized complete block design with three replications was conducted in dasht-e-naz company sari-iran, in 2008. treatments included two planting dates (planting june 7th and 27th), soybean cultivars (bp, jk, 032, 033 and sahar) and herbicide application...

The extent of recovery from stroke is dependent on the survival of neurons, particularly in peri-infarcted regions. Angiogenesis is critical for the development of new microvessels and leads to re-formation of collateral circulation, reperfusion and better recovery. Hyaluronan (HA) is an important component of the brain extracellular matrix and a regulator of cellular differentiation, migration...

Haptokinetic cell migration across surfaces is mediated by adhesion receptors including b1 integrins and CD44 providing adhesion to extracellular matrix (ECM) ligands such as collagen and hyaluronan (HA), respectively. Little is known, however, about how such different receptor systems synergize for cell migration through three-dimensionally (3-D) interconnected ECM ligands. In highly motile hu...

The aim of this study was to deyelop a noyel hydroxyapatite (HA) coating method on zirconia using glass coating technique. A borosi)icate glass, the mixture of the glass ttnd HA (3e, 50, 70, and 90 mass%), and the 100% HA were coated on two kinds of zirconia discs and fired at 900-950'C. After the final coating, the surface of the sample was etched for 3 min in an acid-mixture of 3% HF and 5%HN...

3 The abbreviations used are: ROS, reactive oxygen species; VSMC, vascular smooth muscle cells, HA, hyaluronic acid; DMEM, Dulbecco’s modified Eagle’s medium; FBS, fetal bovine serum; Has2, hyaluronan synthase 2; Hyal3, hyaluronidase 3; LMW-HA, low-molecular-weight HA; HMW-HA, highmolecular-weight HA; DPI, diphenyleneiodonium chloride; DMNQ, 2,3-Dimethoxy-1,4-naphthoquinone; GKT136901 (2-(2-chl...

Grazing systems may alter botanical composition and productivity of grasslands through differential use in time, space, or intensity. Seven simulated grazing treatments were applied six years in eastern Montana, USA to determine effects on plant community composition and standing crop. Treatments were moderate stocking (28.8 AUD ha 1 year ) of cattle using 3-pasture summer rotation, season-long...

4-Methylumbelliferone (4-MU) is a hyaluronic acid (HA) synthesis inhibitor with anticancer properties; the mechanism of its anticancer effects is unknown. We evaluated the effects of 4-MU on prostate cancer cells. 4-MU inhibited proliferation, motility, and invasion of DU145, PC3-ML, LNCaP, C4-2B, and/or LAPC-4 cells. At IC(50) for HA synthesis (0.4 mmol/L), 4-MU induced >3-fold apoptosis in pr...

BACKGROUND Scleroderma (systemic sclerosis; SSc) is a clinically heterogeneous and often lethal acquired disorder of the connective tissue that is characterized by vascular, immune/inflammatory and fibrotic manifestations. Tissue fibrosis is the main cause of morbidity and mortality in SSc and an unmet medical challenge, mostly because of our limited understanding of the molecular factors and s...