BACKGROUND For elderly or medically unfit patients with muscle-invasive bladder cancer, cystectomy or chemotherapy are contraindicated. This leaves radical radiotherapy as the only treatment option. It was the aim of this study to retrospectively analyze the treatment outcome and associated toxicity of conformal versus intensity-modulated radiotherapy (IMRT) using a focal simultaneous tumor boo...

Introduction: Heterogeneity correction is an important parameter in dose calculation for cancer patients where it may be cause inaccuracy in dose calculation as a result of different densities of patients. This study studied the impact of dose calculation of breast cancer patients with and without heterogeneity correction. Material and Methods: Twenty breast cancer patients were treated with Th...

Abstract Background: Radiation induced esophageal toxicity is a primary cause of treatment interruptions in the radiotherapy of lung cancer, for which there are no clear predictive factors. This study attempts to identify risk factors associated with the development of severe radiation induced esophageal toxicity using clinical and dosimetric parameters. Methods: We reviewed the medical records...

background: 3dcrt (three-dimensional conformal radiotherapy) and imrt (intensity-modulated radiotherapy) has provided us with tools to delineate the radiation dose distribution of tumor targets. however, the precision of radiation can be compromised by respiratory motion, which usually limits the geometric and dosimetric accuracy of radiotherapy. the purpose of this study is to evaluate the imp...

BACKGROUND While small improvements in outcome have occurred for patients with locally advanced non-small cell lung cancer (NSCLC), 5-year survival results remain low, ranging from 5% to 20%. Distant metastases and local-regional progression remain significant patterns of failure. METHODS Trials investigating innovative treatment strategies for patients with locally advanced and/or unresectab...

Patients who have undergone solid organ transplants are known to have an increased risk of neoplasia compared with the general population. We report our experience using mediastinal irradiation with helical tomotherapy versus three-dimensional conformal radiation therapy to treat a patient with lung carcinoma 15 years after heart transplantation. Our dosimetric evaluation showed no particular d...

AIMS AND BACKGROUND We compared conformal, intensity-modulated radiotherapy (IMRT) and intensity-modulated arc therapy (IMAT) in early stage glottic cancer in terms of dosimetric features as target coverage, dose to the organs at risk and total treatment time. METHODS AND MATERIALS Five consecutive T1 glottic squamous cell carcinoma patients were selected for the study. Three-dimensional conf...

Introduction:Radiotherapy (RT) plays an important role in treatment of head and neck cancers. In almost 75% of patients with head and neck cancers, RT as the main treatment method is used in order to radical or palliative treatment. Hearing loss is one of the side effects of RT for patients whose inner ear is included in radiation field. The aim of this study was to evaluate th...