نتایج جستجو برای: 3 acetoxypyridine and n 4 acetyl phenyl acetimidic acid pyridine 3 yl ester complex

تعداد نتایج: 17506415  

Journal: :Bioimpacts 2023

Introduction: Imaging a non-small cell lung cancer (NSCLC) using radiolabeled tyrosine kinase inhibitors (TKIs) has attracted attention due to their unique interaction with the target epidermal growth factor receptor (EGFR). Olmutinib (OTB) is one of third-generation EGFR TKIs, which selectively inhibit L858R/T790M mutation. In this study, we aim estimate iodinated OTB (I-OTB)-receptor complex ...

Journal: :Acta Crystallographica Section E Structure Reports Online 2013

Journal: :Acta Crystallographica Section E Structure Reports Online 2012

2012
Guo-Ping Ge Chun-Yan Li Cheng-Hao Gu Mao-He Li Xiao-Nan Xu

In the title complex, [Ir(C(17)H(13)N(2))(2)(C(5)H(7)O(2))], the Ir(III) atom is hexa-coordinated in a distorted octa-hedral geometry by two C,N-bidentate 2-(5-methyl-3-phenyl-pyrazin-2-yl)phenyl (mdpp) ligands and one O,O-bidentate acetyl-acetonate ligand. The dihedral angles between the phenyl rings and the pyrazine ring are 9.56 (14) and 58.99 (14)° for one mdpp ligand and 9.34 (14) and 79.9...

2013
Martha Edith Macías-Pérez Federico Martínez-Ramos Itzia Irene Padilla-Martínez José Correa-Basurto Lowell Kispert Jessica Elena Mendieta-Wejebe Martha Cecilia Rosales-Hernández

NOX (NADPH oxidase) plays an important role during several pathologies because it produces the superoxide anion (O2•-), which reacts with NO (nitric oxide), diminishing its vasodilator effect. Although different isoforms of NOX are expressed in ECs (endothelial cells) of blood vessels, the NOX2 isoform has been considered the principal therapeutic target for vascular diseases because it can be ...

2017
M. J. Corr S. V. Sharma C. Pubill-Ulldemolins R. T. Bown P. Poirot D. R. M. Smith C. Cartmell A. Abou Fayad R. J. M. Goss

Experimental For the synthesis of: Sodium 2'-(Dicyclohexylphosphanyl)-2,6-diisopropyl-(1,1-biphenyl)-4-sulfonate (sXPhos) 12 4 Standard Reaction Procedure of 5-bromoindole 15 under reflux: 5 Microwave Reaction Procedure of 5-bromoindole 15: 5 Standard Microwave Reaction Procedure for Tryptophans: 5 (S)-2-Amino-3-(5-(phenylethynyl)-1H-indol-3-yl)propanoic acid 19 6 (S)-2-Amino-3-5-((3-fluorophen...

Journal: : 2021

А para-chlorophenyl substituent was firstly obtained into the structure of pyridyl-substituted 4-nitrosopyrazole by cyclocondensation hydrazine hydrate with corresponding isonitroso-β-dicarbonyl compounds. The previously unknown 3(5)-(4-chlorophenyl)-5(3)-pyridine-(3(4))-yl-4-nitroso-1H-pyrazoles and 3(5)-alkyl(aryl)-5(3)-pyridine-(3(4))-yl-4-nitroso-1H-pyrazoles is proved studied in detail mod...

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