This observer-blind study (clinicaltrials.gov NCT01462357) compared the immunogenicity and safety of two doses (2D) of the HPV-16/18 AS04-adjuvanted vaccine (2D of AS04-HPV-16/18) vs. two or three doses of the 4vHPV vaccine [2D or 3D of 4vHPV] in 1075 healthy girls aged 9–14 years. Girls were randomized (1:1:1) to receive 2D of AS04-HPV-16/18 at months (M) 0, 6 (N = 359), 2D of 4vHPV at M0, 6 (...

OBJECTIVE The aim of this study was to supplement the paucity of information available on logistical aspects of the application of three-dimensional (3D) mammography in breast screening. METHODS We prospectively examined the effect on radiographers' and radiologists' workload of implementing 3D mammography in screening by comparing image acquisition time and screen-reading time for two-dimens...

This paper proposes a comparative study of 3D and 2D/3D shape descriptors (SDs) for of 3D mesh model indexing and retrieval. Seven state of the art SDs are considered and compared, among which five are 3D (Optimized 3D Hough DescriptorO3DHTD, Extended Gaussian Images EGIs, cords length and spherical angles histograms, random triangles histogram, MPEG-7 3D shape spectrum descriptor – 3DSSD), and...

The immunogenicity of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine (Cervarix®, GlaxoSmithKline Biologicals) administered according to its licensed vaccination schedule (3-dose, 3D) and formulation (20 μg of each HPV antigen; 20/20F) has previously been demonstrated. This partially-blind, controlled, randomized trial (NCT00541970) evaluated 2-dose (2D) schedules using the license...

RATIONALE AND OBJECTIVES Left atrial volume (LAV) measurement by conventional two-dimensional (2D) transthoracic echocardiography (TTE) may be limited by the geometric model, by suboptimal definition of left atrial endocardium, or by chamber foreshortening. Three-dimensional (3D) TTE is posited to eliminate chamber foreshortening, and LAV measurement by 3D TTE should be more reflective of true ...

Automatically synthesizing 3D content from a causal monocular video has become an important problem. Previous works either use no geometry information, or rely on precise 3D geometry information. Therefore, they cannot obtain reasonable results if the 3D structure in the scene is complex, or noisy 3D geometry information is estimated from monocular videos. In this paper, we present an automatic...

Objectives. To determine the existence and extent of ethnic differences in 2D or 3D fetal frontomaxillary facial angle (FMFA) measurements. Methods. During routine 11-14 weeks nuchal translucency screening undertaken in a private ultrasound practice in Sydney, Australia, 2D images and 3D volumes of the fetal profile were collected from consenting patients. FMFA was measured on a frozen 2D ultra...

BACKGROUND The purpose of this study was to assess the correlation between the 2-dimensional (2D) extent of orbital defects and the 3-dimensional (3D) volume of herniated orbital content in patients with an orbital wall fracture. METHODS This retrospective study was based on the medical records and radiologic data of 60 patients from January 2014 to June 2016 for a unilateral isolated orbital...

We use the Glazier-Graner-Hogeweg model to simulate three-dimensional (3D), single-phenotype, avascular tumors growing in an homogeneous tissue matrix (TM) supplying a single limiting nutrient. We study the effects of two parameters on tumor morphology: a diffusion-limitation parameter defined as the ratio of the tumor-substrate consumption rate to the substrate-transport rate, and the tumor-TM...

We present an approach to simultaneously solve the two problems of face alignment and 3D face reconstruction from an input 2D face image of arbitrary poses and expressions. The proposed method iteratively and alternately applies two sets of cascaded regressors, one for updating 2D landmarks and the other for updating reconstructed poseexpression-normalized (PEN) 3D face shape. The 3D face shape...