Circulating microRNAs (miRNAs) hold great promise as easily accessible biomarkers for diverse (patho)physiological processes, including aging. We have compared miRNA expression profiles in cell-free blood from older versus young breast cancer patients, in order to identify "aging miRNAs" that can be used in the future to monitor the impact of chemotherapy on the patient's biological age. First,...

BACKGROUND Focused assessment with sonography for trauma (FAST) has become commonplace in the management of blunt abdominal trauma. However, newer computed tomography (CT) scanners have decreased imaging time for trauma patients and provide more detailed examination of abdominal contents. It was the aim of the current study to evaluate practice patterns of FAST and abdominal CT in blunt trauma ...

Cognitive Approaches to Ancient Religious Experience, edited by Esther Eidinow, Armin W. Geertz, and John North. Cambridge: Cambridge University Press, 2022. xiv + 299 pages, $99.99. ISBN 978-1-316-51533-4.

Konteksty Kultury » 2022 Tom 19 zeszyt 3 „Przybornik nadziei” w czasach namnażajÄ cej się nienawiści Marek Krajewski, (Nie)nawidzenia. Świat przez nienawiść, Universitas, Kraków 2020, ss. 299) A

We identified a new calmodulin kinase I (CaMKI) substrate, cytidyltransferase (CCTα), a crucial enzyme required for maintenance of cell membranes. CCTα becomes activated with translocation from the cytoplasm to the nuclear membrane, resulting in increased membrane phospholipids. Calcium-activated CCTα nuclear import is mediated by binding of its C-terminus to 14-3-3 ζ, a regulator of nuclear tr...

The effects of 5-hydroxytryptamine 1A (5-HT(1A)) receptor ligands on aversive learning were examined in the passive avoidance (PA) task in mice. Anxiety and autonomic functions were investigated using the elevated plus-maze and heart rate measurements. The main findings from this study are as follows. 1) Pretraining administration of the 5-HT(1A) receptor agonist 8-OH-DPAT [8-hydroxy-2-(di-n-pr...

The Problem of Trilingualism Among Ukrainian People Non-Polish Descent in Pavlo Levchuk’s Monograph “Trójjęzyczność ukraińsko-rosyjsko-polska Ukraińców niepolskiego pochodzenia” (Kraków: Księgarnia Akademicka, 2020, ss. 299)The reviewed monograph is the first significant work on phenomenon Ukrainian–Russian–Polish trilingualism people non-Polish descent. contains results research which was cond...