Zarazhenie virusom SARS-CoV-2 proiskhodit ne tol'ko pri neposredstvennom kontakte s inficirovannym chelovekom, no i cherez poverhnosti, kotorymi soprikasalsya bol'noj. Vopros sohraneniya infekcionnogo virusa, sposobnogo zarazit' spustya vremya, ostaetsya otkrytym. Cel'yu issledovaniya bylo izuchit' zhiznesposobnost' na razlichnyh model'nyh poverhnostyah techeniem vremeni. V kachestve materialov...

Human immunodeficiency virus type 1 (HIV-1) infection of most human cells is dependent on cyclophilin A (CypA); however, the opposite phenomenon, known as CypA-dependent inhibition, is also observed in the combination of some capsid (CA) mutations and cell lines. Here, we identified a CA N121K mutant whose infection of 293T, Jurkat, and HeLa cells was impaired by CypA. The N121K mutant could be...

We cloned a cDNA fragment encoding a feline homologue of L-selectin (CD62L). The extracellular region of the feline CD62L fragment contained a calcium-dependent (C-type) lectin domain, an epidermal growth factor-like domain, and two Sushi/CCP/SCR domains. The flow cytometric analysis confirmed that the feline CD62L molecule, which was expressed 293T cells, retained an epitope recognized by an a...