نتایج جستجو برای: 25ohd سرم
تعداد نتایج: 11203 فیلتر نتایج به سال:
BACKGROUND We aimed to examine associations among serum 25-hydroxyvitamin D (25OHD) levels, 1,25-dihyroxyvitamin D (1,25OHD) levels, vitamin D receptor (VDR) polymorphisms, and renal function based on estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes. METHODS In a cross-sectional study of 410 patients, chronic kidney disease (CKD) stage assessed by eGFR was compared...
Severe vitamin D deficiency is common among Muslim immigrants. The dose necessary to correct the deficiency and its consequence for bone health are not known for immigrants. The aim was to assess the effect of relatively low dosages of supplemental vitamin D on vitamin D and bone status in Pakistani immigrants. This 1-year-long randomised double-blinded placebo-controlled intervention with vita...
Some observational studies suggest an inverse association between circulating 25-hydroxyvitamin D (25OHD) and cancer incidence and mortality. We conducted a Mendelian randomization analysis of the relationship between a vitamin D genetic risk score (GRS, range 0-10), comprised of five single nucleotide polymorphisms (SNPs) of vitamin D status in the DHCR7, CYP2R1 and GC genes and cancer risk am...
BACKGROUND Subjects with atopic dermatitis (AD) have defects in antimicrobial peptide (AMP) production possibly contributing to an increased risk of infections. In laboratory models, vitamin D can alter innate immunity by increasing AMP production. OBJECTIVE To determine if AD severity correlates with baseline vitamin D levels, and to test whether supplementation with oral vitamin D alters AM...
BACKGROUND Vitamin D is an important micronutrient for health. Hypovitaminosis D is thought to play a role in the seasonality of a number of diseases and adverse health conditions. To refine hypotheses about the links between vitamin D and seasonal diseases, good estimates of the cyclicality of serum vitamin D are necessary. OBJECTIVES The objective of this study is to describe quantitatively...
BACKGROUND Discharge destination after critical illness is increasingly recognized as a valuable patient-centered outcome. Recently, vitamin D status has been shown to be associated with important outcomes such as length of stay (LOS) and mortality in intensive care unit (ICU) patients. Our goal was to investigate whether vitamin D status on ICU admission is associated with discharge destinatio...
سابقه و هدف: راشیتیسم مرتبط با تومور یکی از انواع نادر راشیتیسم است که در دسته راشیتیسم هیپوفسفاتیک قرار دارد. در این بیماری احتمالاٌ فاکتورهایی توسط تومور آزاد می‌شود که سیستم 1Hydroxyluse 25OHD کلیوی را مهار می‌کنند و باعث کاهش فسفر سرم و بروز علائم بالینی مربوط به راشیتیسم می‌گردند.گزارش مورد: مورد بیماری است که طی 11 سال پیگیری شده و نکته جالب توجه در آن عود علائم کلینیکی راشیتیسم همراه با ع...
OBJECTIVE The increasing incidence of thyroid nodules demands identification of risk factors for malignant disease. Several studies suggested the association of higher TSH levels with cancer, but influence of 25-hydroxyvitamin D (25OHD) is controversial. This study aimed to identify the relationship of thyroid cancer with higher TSH levels and hypovitaminosis D and to evaluate their influence o...
CONTEXT Public health authorities around the world recommend widely variable supplementation strategies for adults, whereas several professional organizations, including The Endocrine Society, recommend higher supplementation. METHODS We analyzed published randomized controlled clinical trials to define the optimal intake or vitamin D status for bone and extraskeletal health. CONCLUSIONS Th...
BACKGROUND Trials in school-aged children suggest vitamin D supplementation reduces asthma exacerbations. Primary aim: to examine whether vitamin D3 (100,000 IU) rapidly raises serum 25-hydroxyvitamin D (25OHD) ≥75 nmol/L in asthmatic preschoolers. METHODS In a double-blind, randomised, placebo-controlled trial, preschool-aged children with asthma received 100,000 IU vitamin D3 (intervention)...
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