BACKGROUND AND PURPOSE CT angiography, CT perfusion, and MR imaging have all been advocated as potentially useful in treatment planning for patients with acute ischemic stroke. We evaluated a large multihospital data base to determine how the use of advanced imaging is evolving in patients treated with intravenous thrombolysis. MATERIALS AND METHODS Patients with acute ischemic stroke receivi...

culum calcium transport by cyclic adenosine monophosphate dependent and calcium–calmodulin-dependent phosphorylations. Biochemistry 1979;18:5150–5157. 30. Kranias EG. Regulation of Ca2þ transport by cyclic 30 ,50-AMP-dependent and calcium-calmodulin-dependent phosphorylation of cardiac sarcoplasmic reticulum. Biochim Biophys Acta 1985;844:193–199. 31. Chu G, Lester JW, Young KB, Luo W, Zhai J, ...

BACKGROUND In spite of its advantageous physiological properties for bioprocess applications, the use of the yeast Kluyveromyces marxianus as a host for heterologous protein production has been very limited, in constrast to its close relative Kluyveromyces lactis. In the present work, the model protein glucose oxidase (GOX) from Aspergillus niger was cloned into K. marxianus CBS 6556 and into K...

Abstract Background Dilated cardiomyopathy is one of the most common cardiomyopathies that at onset shows a with dysfunction, commonly expressed by reduced ejection fraction (EF) and which can lead to heart transplantation. Cardiac "laminopathies" are part complex set CMD. In many cases they show defect in myocardial electrical conduction. Mutations Lamina A / C genes have been associated high ...

Evidence-based medicine (EBM) is delivered through a didactic, blended learning, and mixed models. Students are supposed to construct an answerable question in PICO (patient, intervention, comparison, and outcome) framework, acquire evidence through search of literature, appraise evidence, apply it to the clinical case scenario, and assess the evidence in relation to clinical context. Yet these...

BACKGROUND Obesity is increasing worldwide and weight-control strategies, including the consumption of plant food supplements (PFS), are proliferating. This article identifies the herbal ingredients in PFS consumed for weight control and by overweight/obese dieters in six European countries, and explores the relationship between their consumption and their self-reported BMI. METHODS Data used...

pace 2013;15(Suppl 1):i14–i16. 8. Varma N, Epstein A, Irimpen A, Schweikert R, Shah J, Love CJ. Efficacy and safety of automatic remote monitoring for ICD follow-up: the TRUST trial. Circulation 2010; 122:325–332. 9. Varma N. Rationale and design of a prospective study of the efficacy of a remote monitoring system used in ICD follow-up: the Lumos-T reduces routine office device follow-up study ...