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Since the beginning of XXI century, active research has begun on development fundamentally new radiopharmaceutical drugs based alpha-emitting maternal radionuclides for radionuclide therapy micro-tumors and metastases. The main difficulty in assessing absorbed doses internal irradiation such is to take into account radiation loads from all daughter sequential decay with alpha beta transformatio...

sential role in the survival of multicellular organisms and is observed in a wide variety of physiological situations. Apoptosis is important for biological self-defense, and defects in the ability to undergo apoptosis can lead to various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Apoptosis is a well-defined cellular process characterized by morphological c...

The technique presently used at most millimeter telescopes is the "Chopper Wheel Method" introduced by Penzias and Burrus (ARAA, 1973, 11,51), in which the output de ection of an observed source is compared with the di erence between the sky brightness and that of an ambient temperature load. The physical temperature of the absorbing atmosphere is then taken to be the same as the ambient load o...

OBJECTIVE To analyze resectability and survival in patients with hilar cholangiocarcinoma according to a proposed preoperative staging scheme that fully integrates local, tumor-related factors. SUMMARY BACKGROUND DATA In patients with hilar cholangiocarcinoma, long-term survival depends critically on complete tumor resection. The current staging systems ignore factors related to local tumor e...

Objective To evaluate neuropathic pain and peripheral vascular disease in diabetics and compare this with the length of time since diagnosis in type 1, and type 2 diabetes. Methods A cross-sectional study with 225 diabetics chosen from their responses on the DN4 questionnaire, who were then evaluated with the ankle-brachial index (ABI), separating type 1 diabetes from type 2 diabetes. Resul...