Objective(s):This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on pyramidal neurons of hippocampus in 18 and 32 day mice offspring. Materials and Methods: Thirty female mice were randomly allocated into cases and controls. In case group, animals received morphinesulfate 10 mg/kg.body weight intraperitoneally during 7 days bef...

The objective of this prespecified TRINITY study subgroup analysis was to assess the efficacy and safety of triple-combination treatment with olmesartan medoxomil (OM) 40 mg, amlodipine besylate (AML) 10 mg, and hydrochlorothiazide (HCTZ) 25 mg vs the component dual-combination treatments in obese (body mass index [BMI] ≥30 kg/m(2) ) and nonobese (BMI <30 kg/m(2) ) hypertensive participants. Th...

BACKGROUND Although systemic inflammation is believed to cause upregulation of nicotinic acetylcholine receptors (nAchRs) in muscle, chronic infections such as Chagas' disease occasionally are complicated by myasthenia gravis. The authors investigated how a nonlethal cecal ligation and puncture (CLP) peritonitis model in rats could affect muscle nAchR. METHODS On day 1, 4, 7, 14, or 21 after ...

One hundred forty-seven patients with hematologic diseases and treated by allogeneic marrow transplants received graft-versus-host disease (GVHD) prevention with methotrexate and cyclosporine. In addition, 73 of the 147 patients were randomized to receive methylprednisolone during the first 35 days after transplant to improve GVHD prevention, whereas 74 patients were randomized not to receive m...

Back ground: Split thickness grafting is a routinely done procedure in treatment of burn and coverage other wounds. These patients require management both donor site grafted area. Donor wound may be more painful distressing as compared to the patient´s skin area there additional scarring. Different types dressing are used for healing SSG Aim: To compare conventional Suprathel at terms total con...

Using field observations of ~15 wild adult black bear (Ursus americanus kermodei) foraging on a salmon stream during two autumns on the central coast of British Columbia, we tested for laterality of forelimb use during lunging and during handling of salmon. Of 288 lunging events observed overall, 53% were non biased, 26% were right-limb biased, and 21% left-limb biased (p = .53 between left and...

The toxic effects of morphine sulfate in the adult cerebral cortex and one-day neonatal cerebellum have been studied. This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on the Purkinje cells and cerebellar cortical layer in 18- and 32-day-old mice offspring. Thirty female mice were randomly allocated into cases and controls. I...

Hemolysis is a common complication associated with mortality on extracorporeal membrane oxygenation (ECMO). Plasma-free hemoglobin (PFH) the most commonly used biomarker reported for hemolysis ECMO. This test not readily available at all institutions, and other more tests may indicate nearly as well or PFH. The purpose of this study was to correlation biomarkers PFH All patients younger than 21...

OBJECTIVE To study the effect of an educational intervention on the management of hospitalized infants with bronchiolitis. DESIGN Sequential, prospective cohort study. SETTING A 235-bed children's hospital with nearly all private rooms. PATIENTS Consecutively admitted, previously healthy children younger than 24 months with symptoms of bronchiolitis. The first cohort was enrolled between ...

Purpose: This study was conducted to develop and examine the effects of a nursing education program using virtual reality enhance clinical decision-making ability in respiratory disease care by assessing students’ confidence performance, ability, practice flow, class evaluations, simulation design evaluations.Methods: developed based on Jeffries model 5E learning cycle model, blending high-fide...