widely in nature and have unique biological activities. Recently, Naganuma and his colleagues found that three natural triterpenes, betulin (1), uvaol (2), and soyasapogenol B (3), have reducing effects against the toxicity of cadmium chloride in HepG2 cells (Fig. 1). They also reported that betulin induced certain proteins, though not metallothionein, which is the representative protein in red...

the therapeutic value of kids’ artistic activities has always attracted experts and medics’ attention. it has a lot of usages in obtaining peace of mind and health in children. art therapy is a new and organized way in solving social and mental problems and disorders that can lead to improvement, especially in children. school anxiety can be seen and reduced, in artistic activities, as a sign o...

UFT, a mixture of FT -207 and uracil in a molar ratio 1 : 4, has been noticed to have the higher antitumor activity to various tumors other than FT-207. We studied the pharmacodynamics of UFT (900 mg for FT-207) after oral administration on 3 cases of malignant glioma and 4 cases of metastatic brain tumor by using high performance liquid chromatography, and the following results obtained; 1. Mo...

(‡) Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT U.K. (||) Lipoprotein Group, MRC Clinical Sciences Centre, Hammersmith Hospital, Ducane Road, London W12 ONN U.K. (¶) Metabolic Research Laboratory, Nuffield Dept of Clinical Medicine, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE U.K. (§) To whom correspondence should be address...

INTRODUCTION Characteristics of Monoclonal Antibodies, 203 Production of Monoclonal Antibodies, 207 Developing the Screening Method, 207 Generating Hybridomas, 216 Preparation for Fusions, 217 Fusions, 220 Plating Strategies, 222 Feeding Hybridomas, 224 Supernatant Collection Strategies for Screening, 224 Screening, 225 Expanding and Freezing Positive Clones, 225 Dealing with Contamination, 229...