Hydrogen cyanide is readily detected in the headspace above Pseudomonas aeruginosa cultures and in the breath of cystic fibrosis (CF) patients with chronic (P. aeruginosa) infection. We investigated if exhaled breath HCN is an early marker of P. aeruginosa infection. 233 children with CF who were free from P. aeruginosa infection were followed for 2 years. Their median (interquartile range) age...

1. Minniti S, Vincentini S, Procacci C. Congenital anomalies of the venae cavae: embryological origin, imaging features and report of three new variants. Eur Radiol 2002; 12: 2040–2055. 2. Nsah EN, Moore GW, Hutchins GM. Pathogenesis of persistent left superior vena cava with a coronary sinus connection. Pediatr Pathol 1991; 11: 261–269. 3. Pasquini L, Belmar C, Seale A, Gardiner HM. Prenatal d...

In the present study, we investigated the effects of acute intracerebroventricular (icv) insulin administration on central mechanisms regulating urinary sodium excretion in simultaneously centrally NG-nitro-L-arginine methylester (L-NAME)-injected unanesthetized rats. Male Wistar-Hannover rats were randomly assigned to one of five groups: a) icv 0.15 M NaCl-injected rats (control, N = 10), b) i...

Differences between the structures of bacterial, archaeal, and eukaryotic ribosomes account for the selective action of antibiotics. Even minor variations in the structure of ribosomes of different bacterial species may lead to idiosyncratic, species-specific interactions of the drugs with their targets. Although crystallographic structures of antibiotics bound to the peptidyl transferase cente...

Counts of nest starts are often used as indicators of the size of avian nesting populations, or of avian productivity. However, the accuracy of single or repeated counts of unmarked nests over time for estimating seasonal numbers of nests may be strongly affected by nest events that fall in between survey dates, or that occurred prior to or after the survey period. Accuracy may also be affected...

The discovery of over 200 extrasolar planets with the radial velocity (RV) technique has revealed that many giant planets have large eccentricities, in striking contrast with most of the planets in the solar system and prior theories of planet formation. The realization that many giant planets have large eccentricities raises a fundamental question: “Do terrestrial-size planets of other stars t...

Flows along the upper Qu’Appelle River are expected to increase in the future via increased discharge from Lake Diefenbaker to meet the demands of increased agricultural and industrial activity and population growth in southern Saskatchewan. This increased discharge and increased air temperature due to climate change are both expected to have an impact on the water quality of the river. The Wat...

This study aimed to describe past time trends of the prevalence of former smokers in Italy and to estimate prevalence projections using a Bayesian approach. An age-period-cohort (APC) analysis has been carried out in order to investigate the effect of the age, period and birth cohort on the prevalence of former smokers during 1980-2009. A Bayesian APC model with an autoregressive structure for ...

A method for estimating uncertainty in future climate change is discussed in detail and applied to predictions of global mean temperature change. The method uses optimal fingerprinting to make estimates of uncertainty in model simulations of twentieth-century warming. These estimates are then projected forward in time using a linear, compact relationship between twentieth-century warming and tw...

This study addresses the greatest concern facing the large-scale integration of wind, water, and solar (WWS) into a power grid: the high cost of avoiding load loss caused by WWS variability and uncertainty. It uses a new grid integration model and finds low-cost, no-load-loss, nonunique solutions to this problem on electrification of all US energy sectors (electricity, transportation, heating/c...