Leishmaniasis is a major public health problem in various part of world; it has also emerged in new geographic areas and host populations. Visceral infection can remain subclinical or become symptomatic, with an acute, subacute or chronic course. Kala-azar, or visceral leishmaniasis (VL), presents as fever, pancytopenia and hypergammaglobulinaemia. The presence of splenomegaly is characteristic...

Thirty cases of human kala-azar were diagnosed by iliac crest biopsy and myeloculture. Histological analysis of 12 patients showed diffuse thickening of reticulin fibers. To the best of our knowledge, this is the third report describing secondary bone marrow fibrosis (myelofibrosis-like) associated with kala-azar. Patients with positive bone marrow fibrosis (pbmf = 12) were compared to patients...

Although liposomal amphotericin B (AmBisome) is considered as the first-line treatment for New Kala-azar, there is not enough evidence on the dosage formulation in children and its effect on them. Being considered as the safest drug for treatment of Kala-azar, this case of AmBisome-induced avascular necrosis now gives rise to the question; whether it is actually safe enough and if a dosage modi...

In Brazil, visceral Leishmaniasis is caused by Leishmania chagasi. The development of cutaneous lesions in visceral leishmaniasis patients has been described in two different clinical contexts. Patients with compromised immunity can develop skin lesions as a direct consequence of a current visceral disease. Equally, patients with a history of kala-azar and progressive, immune improvement occasi...

Computer-assisted pronunciation tutoring (CAPT) methods have been well-established in research and education. Common system approaches include the phonetic quality assessment, highlight problematic sections in the speech signal and usually rely on automatic speech recognition (ASR) regarding the target language L2. The contribution deals with the audiovisual CAPT system AzAR. An extensive feedb...

The incidence of infantile visceral leishmaniasis is currently increasing, at least in the Mediterranean region. Most cases seen in France occur on the Mediterranean coast or are imported from Africa. However, contamination in other regions of France is not an exceptional occurrence and may raise diagnostic problems. The parasite reservoir is the dog population in which the prevalence of Leishm...

had several private cases sent to us by private practitioners of the city. Almost all those cases were in the initial stages. The peripheral blood of these patients was examined every week (each time about ̂ dozen slides), but I rarely found the parasites in the early stages. Still, other changes in the blood and the characteristic temperature of the disease made us suspect a case to be one of K...

Kala-azar or visceral leishmaniasis is usually associated with progressive emaciation in spite of the fact that the patients generally have a good, at times voracious, appetite and their diet is not often greatly restricted. Apart from emaciation, signs of avitaminosis, viz, xerophthalmia, Bitot's spots, glossitis, angular stomatitis, dryness of the skin, etc., have often been noticed by one of...

During the session of the Congress of the Far Eastern Association of Tropical Medicine held at Calcutta in December 1927, Lieut.-Co . B. N. Chopra of the Calcutta School of Tropical Medicine demonstrated a simple te> 01 diagnosing kala-azar. With a view to find on its efficiency 1 undertook to carry out som* control tests in a non-kala-azar distric ? part of this work was commenced in April 192...