In this issue, Doucette and colleagues demonstrate that information related to whether an odor is currently linked to reward can be observed uniquely in population activity in the olfactory bulb, changing our understanding both of what is coded by the first olfactory relay in the CNS and of how this coding is instantiated.

I have read with interest the recent paper by Liu and Zhang [1] on the putative association of the PRSS1 gene with pancreatitis. In their article, the authors claim a highly significant association based on a meta-analysis of seven previous case-control studies. Their methodological approach, however, warrants a cautionary comment. To assess the impact of PRSS1 mutations, the authors have conce...

• Compose personalized documents for the reader. For example, once could have a text base on statistical methods, where each topic is treated at several levels (such as for readers who know calculus and those who do not) and where each method has examples from several domains. Given a reader’s background, subject domain, and learning goal, the system would then sequence of topics that build on ...