The potential of predicting druggability for a particular disease by integrating biological and computer science technologies has witnessed success in recent years. Although the computer science technologies can be used to reduce the costs of the pharmaceutical research, the computation time of the structure-based protein-ligand docking prediction is still unsatisfied until now. Hence, in this ...

Background Lymphedema, refractory to non-operative methods [1], may be managed by surgical treatment. Indications include insufficient lymphedema reduction by well performed medical and physical therapy (less than 50%), recurrent episodes of lymphangitis, intractable pain, worsening limb function, patient unsatisfied of the results obtained by non-operative methods and willing to proceed with s...

At zero temperature, the 3-state antiferromagnetic Potts model on a square lattice maps exactly onto a point of the 6-vertex model whose long-distance behavior is equivalent to that of a free scalar boson. We point out that at nonzero temperature there are two distinct types of excitation: vortices, which are relevant with renormalization-group eigenvalue 1 2 ; and non-vortex unsatisfied bonds,...

BACKGROUND Young breast cancer survivors have specific needs related to age. Clarifying the relationships between unmet information needs and quality of life (QOL) in young breast cancer survivors can contribute to constructing a support system to enhance QOL in patients. OBJECTIVE This study aimed to identify the unmet information needs and examine the relationships between unmet information...

This research examined the mediatory role of life purpose and career indecision in the relationship between the satisfaction of basic psychological needs and aggression. Data were collected from high school students (n = 466) and results showed that life purpose and career indecision fully mediated the relationship between basic psychological needs satisfaction and aggression. These findings su...

OBJECTIVE The objective of this study was to evaluate the financial characteristics and level of satisfaction of physicians practicing in Lebanon. METHODS We conducted an anonymous, interviewer-administered phone survey of physicians practicing medicine in Lebanon. We conducted both descriptive and regression analyses. RESULTS Of 778 invited physicians, 546 participated in the survey (70% r...

BACKGROUND There are growing concerns about developmental, behavioural, social and emotional wellbeing of children throughout the world. A huge gap exists between the instructions provided on medical disciplines and on areas of Developmental-Behavioural Pediatrics (DBP) during pediatric training in our region. OBJECTIVE This study aims to evaluate the Developmental-Behavioural pediatrics (DBP...

BACKGROUND During the past decade, the use of stored tissue has become an object of increased ethical query. A Swedish biobank and a biotech company have been praised for solving the ethical problems with explicit informed consent procedures, and we decided to investigate donors' perceptions of the system. METHODS A questionnaire was sent to a randomized sample of 1200 donors who had donated ...

Aims Recruitment and retention of medical staff is a national issue. Low level means challenges in provision adequate efficient patientcare. There lack flexibility for clinicians to get time Supported Programmed Activity (SPA). Burn out existing loosing good will common which increases patients’ complaint potential risk near misses serious incidents. Leicestershire Partnership NHS Trust (LPT) h...

Chronic plaque psoriasis is a systemic disease affecting over 3% of the population, and many patients are unsatisfied with their current treatment regimen. With advances in understanding of the pathophysiology of psoriasis, new therapeutic options are being developed. The newest of these agents, ustekinumab, offers patients rapid results and the convenience of four annual subcutaneous doses, wi...