The concept of using natural orifices to reduce the complications of surgery, Natural Orifices Transluminal Endoscopic Surgery, has also been applied to therapeutic endoscopy. Endoscopic submucosal surgery (ESS) provides more treatment options for various gastrointestinal diseases than traditional therapeutic endoscopy by using the submucosal layer as a working space. ESS has been performed in ...

Enterokinase was measured in peroral intestinal biopsies showing normal histology and in those from untreated coeliac patients which showed gross villous atrophy. There was no significant difference in the specific activity of enterokinase between these two groups. These results do not support the recent hypothesis that enterokinase is a brush border enzyme, but would be consistent with the ide...

Diabetic gastroparesis is a chronic functional syndrome caused by diabetes mellitus. Diagnosis is based on symptoms and scintigraphy. The therapeutic options are still limited. A publication has recently described the effectiveness of gastric per oral endoscopic myotomy. We herein present a case of diabetic gastroparesis treated by gastric peroral endoscopic myotomy which extended the submucosa...