نتایج جستجو برای: 188re

تعداد نتایج: 147  

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011
Federica Orsini Federica Guidoccio Sara Mazzarri Giuliano Mariani

UNLABELLED This retrospective study compared the effects of single and multiple administrations of (186)Re-hydroxyethylidenediphosphonate ((186)Re-HEDP) on palliation and survival of prostate cancer patients presenting with more than 5 skeletal metastases. METHODS A total of 60 patients were divided into 3 groups. Group A (n = 19) consisted of patients who had received a single injection; gro...

Journal: :journal of biomedical physics and engineering 0
hr baghani phd student of radiation medicine, radiation medicine department, shahid beheshti university, tehran, iran ar nazempour msc student of radiation medicine, radiation medicine department, shahid beheshti university, tehran, iran smr aghamiri professor of radiation medicine, radiation medicine department, shahid beheshti university, tehran, iran sm hosseini daghigh phd student of radiation medicine, radiation medicine department, shahid beheshti university, tehran, iran aa mowlavi professor of nuclear physics, physics department, school of science, hakim sabzevari university, sabzevar, iran

background and objective: the most common intravascular brachytherapy sources include 32p, 188re, 106rh and 90sr/90y. in this research, skin absorbed dose for different covering materials in dealing with these sources were evaluated and the best covering material for skin protection and reduction of absorbed dose by radiation staff was recognized and recommended. method: four materials includin...

Journal: :Physics in medicine and biology 2012
N Lanconelli M Pacilio S Lo Meo F Botta A Di Dia A Torres Aroche M A Coca Pérez M Cremonesi

The increasing availability of SPECT/CT devices with advanced technology offers the opportunity for the accurate assessment of the radiation dose to the biological target volume during radionuclide therapy. Voxel dosimetry can be performed employing direct Monte Carlo radiation transport simulations, based on both morphological and functional images of the patient. On the other hand, for voxel ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Guozheng Liu Shuping Dou George Mardirossian Jiang He Surong Zhang Xinrong Liu Mary Rusckowski Donald J Hnatowich

PURPOSE Pretargeting has been attracting increasing attention as a drug delivery approach. We recently proposed Watson-Crick pairing of phosphorodiamidate morpholino oligomers (MORF) for the recognition system in tumor pretargeting. MORF pretargeting involves the initial i.v. injection of a MORF-conjugated antitumor antibody and the subsequent i.v. injection of the radiolabeled complement. Our ...

Journal: :Annals of nuclear medicine 2009
Kazuma Ogawa Hidekazu Kawashima Seigo Kinuya Kazuhiro Shiba Masahisa Onoguchi Hiroyuki Kimura Kazuyuki Hashimoto Akira Odani Hideo Saji

OBJECTIVE Rhenium is one of the most valuable elements for internal radiotherapy because (186)Re and (188)Re have favorable physical characteristics. However, there are problems when proteins such as antibodies are used as carriers of (186/188)Re. Labeling methods that use bifunctional chelating agents such as MAG3 require the conjugation of the (186/188)Re complex to protein after radiolabelin...

2011
Chia-Che Tsai Chih-Hsien Chang Liang-Cheng Chen Ya-Jen Chang Keng-Li Lan Yu-Hsien Wu Chin-Wei Hsu I-Hsiang Liu Chung-Li Ho Wan-Chi Lee Hsiao-Chiang Ni Tsui-Jung Chang Gann Ting Te-Wei Lee

BACKGROUND Nanoliposomes are designed as carriers capable of packaging drugs through passive targeting tumor sites by enhanced permeability and retention (EPR) effects. In the present study the biodistribution, pharmacokinetics, micro single-photon emission computed tomography (micro-SPECT/CT) image, dosimetry, and therapeutic efficacy of (188)Re-labeled nanoliposomes ((188)Re-liposomes) in a C...

2002
Yasushi Arano Yasushi ARANO

Technetium-99m (99mTc) is one of the most desirable radionuclides for external imaging in diagnostic nuclear medicine, due to the emission of gamma ray of optimal energy (140 keV), a suitable half-life (6 h), and availability from 99Mo-99mTc generator systems. In addition, development of 99mTc radiopharmaceuticals for tumor imaging paves the way for therapeutic radiopharmaceuticals with high en...

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