نتایج جستجو برای: 17 estradiol

تعداد نتایج: 302835  

Journal: :Cancer research 1984
B Fisher N Gunduz E A Saffer S Zheng

A variety of hormones have been implicated in the process of liver regeneration. Despite the demonstration of specific estrogen receptors (ER) in mammalian liver and the identification of responses to estrogen which occur in liver, there has been little or no investigation of the relation of that hormone or its receptor to liver regeneration or liver growth. This report provides information whi...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2003
Tomoko Okubo Itsu Kano

Estrogenic activities of more than 90 chemicals including food additives, foodstuffs of plant origin, and some chemicals, which could be orally ingested, were examined by assaying estrogen receptor (ER)-dependent proliferation of MCF-7 cells. Among 66 food additives, 17 compounds stimulated the proliferation, but their concentrations giving maximal cell yield were higher than that of 17 beta-es...

Journal: :Zeitschrift fur Naturforschung. Section C, Biosciences 1979
K Pollow W Elger H Hesslinger B Pollow

17 beta-Hydroxysteroid dehydrogenase activity towards estradiol-17 beta has been demonstrated in the 105,000 x g supernatant of rabbit uterus. Hydroxylapatite chromatography of the enzyme activity isolated by ammonium sulfate precipitation, gel filtration and DEAE-cellulose chromatography yielded a single 17 beta-hydroxysteroid dehydrogenase activity. Further purification of the enzyme preparat...

Journal: :Cancer research 1986
B M Arafah P Griffin N H Gordon O H Pearson

Cells obtained from freshly resected human breast cancer were grown in vitro utilizing the soft agar technique. The effects of adding an antiestrogen (tamoxifen, TAM) and 17 beta-estradiol alone or simultaneously on cell growth were assessed. The addition of TAM (10(-6) M) to the medium resulted in a significant decrease in cell growth in 26 of 36 (72%) estrogen receptor (ER)-positive tumors an...

Journal: :physiology and pharmacology 0
zeinab sharifkhodaei department of biology, science and research branch, islamic azad university, tehran, iran nasser naghdi department of physiology and pharmacology, pasteur institute of iran, tehran 13164, iran shahrbanoo oryan department of biology, tarbiat moalem university, tehran, iran parichehr yaghmaei department of biology, tarbiat moalem university, tehran, iran

introduction: neurohormones like testosterone and estradiol have an important role in learning and memory. the hippocampus is essentially involved in learning and memory, and is known to be a target for estradiol actions. estrogen receptors (ers) are highly expressed in ca1 of rat hippocampus, and mediate the effects of estrogen on learning and memory. estradiol receptor belong to a family of t...

Journal: :The Journal of clinical investigation 1989
S C Cooper D A Roncari

Having reported that omental preadipocytes from massively obese persons release into the culture medium proteins mitogenic for preadipocytes, this study aimed to determine whether estrogens contribute to the production of these factors. Sub-cultured omental preadipocytes from 13 massively obese women were grown in the presence or absence of 17-beta-estradiol, and during the last 24 h the condit...

Journal: :Journal of atherosclerosis and thrombosis 2012
Marco Matteo Ciccone Ettore Cicinelli Alessio Giovanni Pietro Scicchitano Michele Gesualdo Annapaola Zito Fara Fornarelli Manuela Locorotondo Maria Vittoria Cicinelli Concetta Di Teo Giuseppe Farinola Domenico Scrutinio

AIM The study aim was to evaluate the acute hemodynamic effects of intranasal 17-beta-estradiol on ophthalmic arterial circulation in postmenopausal women. METHODS Twenty-one healthy women in natural menopause for at least 6 months (mean age: 53.2± 2.9 years) were investigated. Each patient received 300 µg intranasal 17-beta-estradiol. We evaluated the heart rate, systolic and diastolic blood...

abolhassan Ahmadiani, Azadeh Abdi, Fariba Khaodagholi, fatemeh mohagheghi, Habibollah Peirovi, Leila Dargahi, Leila Khalaj,

Introduction: Postoperative neurological deficit is the most devastating complication after thoracoabdominal aortic aneurysm repair. Despite demonstrated neuroprotective effects of estradiol, its protective efficacy against spinal cord ischemia-reperfusion and underlying mechanisms are not yet elucidated. Methods: Two groups, each of 10 New Zealand white male rabbits, were studied. Control g...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2002
J Andrew Williams Barbara J Ring Varon E Cantrell Kristina Campanale David R Jones Stephen D Hall Steven A Wrighton

Previous results demonstrating homotropic activation of human UDP-glucuronosyltransferase (UGT) 1A1-catalyzed estradiol-3-glucuronidation led us to investigate the effects of 16 compounds on estradiol glucuronidation by human liver microsomes (HLM). In confirmation of previous work using alamethicin-treated HLM pooled from four livers, UGT1A1-catalyzed estradiol-3-glucuronidation demonstrated h...

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