Introduction: Recently, 166Ho-BPAMD was introduced as a suitable agent for bone marrow ablation. The aim of this study was to estimate the absorbed dose of this novel agent in the human organs which is necessary before the clinical application. Methods: 166Ho was produced by direct irradiation of 165Ho in the research reactor. 250 µg...

BACKGROUND Matrix metalloproteinases (MMPs) are enzymes involved in the proteolytic degradation of extracellular matrix. They play an important role in several disease processes, such as inflammation, cancer, and atherosclerosis. METHODS AND RESULTS In this study, we have used the broad-spectrum MMP inhibitor CGS 27023A to develop the radioligand [123I]I-HO-CGS 27023A for in vivo imaging of M...

Visual object tracking is one of the most vigorous research area in Computer Vision. A lot of algorithms already achieve high performance and accuracy. Whereas, most of visual object tracking algorithms proceed separately from detection algorithm because of difference between tracking and detection descriptor. Instead, we propose adaptive cell-size HoG (acHoG) based Particle Filter Tracking (PF...

A new radical mechanism of nucleotide polymerization is found. The finding is based on the Car-Parrinello molecular dynamics computations at 310 K with an additional spin-spin coupling term for 31P and 1H atoms and a radical pair spin term included. The mechanism is initiated by a creation of a high-energy spin-separated Mg-ATP complex in a triplet state in which the Mg prefers an uncommon chel...

We compared saline (S) and sodium dodecyl sulphate (SDS) extracts from Taenia solium (homologous species - HO) and Taenia crassiceps (heterologous species - HE) metacestodes in order to detect IgG by ELISA and immunoblot assay (IBA) in cerebrospinal fluid (CSF) for the diagnosis of human neurocysticercosis (NC). CSF samples were obtained from 93 patients. Of these, 40 had NC, five had a diagnos...

Hyung-Ho Kim, Sang-Uk Han1, Min-Chan Kim2, Woo Jin Hyung3, Wook Kim4, Hyuk-Joon Lee5, Seung Wan Ryu6, GyuSeok Cho7, Chan Young Kim8, Han-Kwang Yang5, Do Joong Park, Kyo Young Song9, Sang IL Lee10, Seong Yeob Ryu11, Joo Ho Lee12; Korean Laparoscopic Gastrointestinal Surgery Study (KLASS) Group Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of...

Rational combination of pyridazine, hydroxo and carboxylate bridging ligands led to the assembly of three types of mixed-ligand polynuclear Cu(II) clusters (A: [Cu2(μ-OH)(μ-pdz)(μ-COO)]; B: [Cu4(μ3-OH)2(μ-pdz)2]; C: [Cu5(μ-OH)2(μ-pdz)4(μ-COO)2(μ-H2O)2]) and their integration into 3D framework structures. Mixed-ligand complexes [Cu2(μ-OH){TMA}(L)(H2O)] (1), [Cu4(μ3-OH)2{ATC}2(L)2(H2O)2]·H2O (2) ...

BACKGROUND Abundance of commensals constituting the intestinal microbiota (IM) affects the immune system and predisposes to a variety of diseases, including intestinal infections, cancer, inflammatory and metabolic disorders. Housing conditions determine the IM and can hence influence the immune system. We analyzed how both variables affect the IM of four immune-compromized mouse lines kept und...

☆ This work was supported by a grant of The Advancing Safe Transportation throughout the Lifespa G-0058) to MB, a fellowship from the Swiss Nationa (PA001-117473) to SMJ, and a grant from the Office o (N00014-09-0213). Study 2 was conducted as a part with the guidance of the other co-authors and wit University of Bern and the National Taiwan Normal U wish to thank Chao-Yi Ho and Philip Cheng fo...

The purpose of this study is to compare three-dimensional conformal radiotherapy (3D-CRT) plans in a setting of salvage radiotherapy after radical prostatectomy (RP) and to simulate whether dose escalation is possible with the most adequate 3D-CRT technique. This study included consecutive 10 patients underwent salvage radiotherapy (RT) for biochemical relapse of prostate cancer after RP. Norma...