We present radio observations at three frequencies and contemporaneous optical monitoring of the peculiar BLLac object AO0235+164. During a three-week campaign with the VLA we observed intraday variability in this source and found a distinct peak which can be identified throughout the radio frequencies and tentatively connected to the R-band variations. This event is characterized by unusual pr...

Diskhaler (FP-DH), developed for inhalation of corticosteroids, is widely used for the treatment of asthma. A dry powder inhaler (DPI) is a breath controlled drug delivery system, in which a turbulent airstream is created by exploiting the patient’s own inspiratory flow rate and is required to aerosolize particles for inhalation at a satisfactory peak inspiratory flow rate, which can achieve su...

Cigarette smoke is a profound proinflammatory stimulus that causes acute lung inflammation and chronic lung disease, including chronic obstructive pulmonary disease (COPD, emphysema, and chronic bronchitis), via a variety of mechanisms, including oxidative stress. Cigarette smoke contains high levels of free radicals, whereas inflammatory cells, including macrophages and neutrophils, express en...

BACKGROUND Diabetic retinopathy (DR) is the most common microvascular complication of diabetes. It can lead to significant visual loss. The aim of this study was to determine the frequency and clinical profile of diabetic retinopathy, and assess the outcomes of laser photocoagulation therapy in a diabetic population in Cameroon. METHODS We carried out a prospective cohort study during 24 mont...

A novel aerobic, Gram-negative bacterium, named 13IX/A01/164(T), was isolated from surface waters in the coastal north-western Mediterranean Sea. Cells were motile, straight rods, 2.5 mum long and 0.2 mum wide, and formed orange colonies on marine agar medium. The G+C content of the genomic DNA of strain 13IX/A01/164(T) was 42 mol%. Phylogenetic analysis of the 16S rRNA gene sequence placed the...

INTRODUCTION 152 GUIDE TO TYPICAL FEEDSTUFFS 153 Cereals, sugar beet and oil seeds as feedstuffs 154 Major cereals fed to horses 154 Oil seeds 156 Vegetable oils 156 Forages and other fiber sources 158 Hay 158 Soaking hay before feeding 159 Semi-wilted forages 159 Silage 159 Straw 160 Hydroponics 160 Soya hulls and sugar beet pulp 161 Methods of feed processing 161 Feed storage 162 Feedstuffs a...

Protein Therapeutics versus Small Molecule Drugs .............................................. 154 Sources of Protein Therapeutics ................................................................... 155 Targets of Protein Therapeutics and Modes of Action .................................. 155 Engineering Effective Protein Therapeutics .......................................................... ...

The mechanism of augmentation of tumor cell killing by immune effector cells and chemotherapeutic drugs was studied. The effect of treating tumor cells with various antineoplastic drugs on their sensitivity to murine natural cell-mediated cytotoxicity in vitro was investigated. Pretreatment with actinomycin D at nontoxic concentrations rendered L929 and WEHI-164 tumor cells more susceptible to ...

Bone marrow-derived mesenchymal stem cells (BMSCs) have been shown to be able to migrate towards glioma, but the molecular mechanisms responsible for this migratory behavior still require further elucidation. This study aimed to test the role of vascular endothelial growth factor (VEGF) in the C6 glioma-induced migration of BMSCs, evaluate the effect of VEGF on the migratory capacity and vascul...

The Neu (ErbB2, HER2) member of the epidermal growth factor receptor family is implicated in many human breast cancers. We have tested the importance of increased angiogenic signaling in the NeuYD [mouse mammary tumor virus (MMTV)-Neu(ndl)-YD5] mammary tumor model. Transgenic mice expressing vascular endothelial growth factor (VEGF)(164) from the MMTV promoter were generated. These mice express...