Ketumbar biasa digunakan sebagai bahan rempah rumah tangga. Komposisi minyak ketumbar adalah 60-70% senyawa linalool. Senyawa linalool mempunyai efek sedatif sehingga dapat menjadi alternatif pengobatan penyakit psikis. Telah dilakukannya ekstraksi pada biji dan uji pengaruh sedatifnya diharapkan menaikkan nilai jual ketumbar. Penelitian ini bertujuan untuk mengetahui dari yang diekstrak ketumb...

Pregnant Sprague-Dawley rats were exposed to ethylbenzene (EB; 0, 250, or 1000 ppm) and methylethylketone (MEK; 0, 1000, or 3000 ppm), alone and in combination, by inhalation, for 6h/day, during days 6-20 of gestation. Maternal toxicity, evidenced by decreased in body weight gain and food consumption, tended to be greater after simultaneous exposures to the high concentrations of 1000 ppm EB an...

Lead has been shown to exert toxic effects during early development. In these in vivo and ex vivo experiments, the effect of lead on the immune system of the developing embryo was assessed. Nine-week-old female Fischer 344 rats were exposed to lead acetate (0, 100, 250, and 500 ppm lead) in their drinking water during breeding and pregnancy (exposure was discontinued at parturition). Offspring ...

Ethanol (ETOH) is added to unleaded gasoline to decrease environmental levels of carbon monoxide from automobiles emissions. Therefore, addition of ETOH in reformulated fuel will most likely increase and the involuntarily human exposure to this chemical will also increase. This preliminary study was undertaken to evaluate the possible neuromotor effects resulting from acute ETOH exposure by inh...

abstract in the present research the effect of different concentrations of cr3+ on growth and uptake of chromium by mycelium of agaricus bisporus was investigated. chromium playes an important role in improvment of insulin action in diabetic patients. the aim of this research was to investingate tolerance threshold of the fungus to cr3+ concentrations. mycelium of a. bisporus was cultured in so...

Exposure of mice to 1000 ppm of vinyl chloride (VC), 6 hr/day, 5 days/week, caused some acute deaths with toxic hepatitis and marked tubular necrosis of the renal cortex. Starting the sixth month, mice exposed to 1000, 250, or 50 ppm of VC became lethargic, lost weight quickly, and died. Only a few mice exposed to 50 ppm survived for 12 months. Pulmonary macrophage count was elevated in some mi...

background: investigation of toxicity of silver nanoparticle, especxially blood toxicity, is necessary because this nanoparticle is used a lot in diffrerent parts of life and invironment. the aime of this is evaluation the effects of silver nanoparticles with different concentrations on blood cells pregnant wistar rats. materials and methods: in this case control study, 30 pregnant rat were div...

The purpose of this study was to evaluate the effects of L-carnitine fed during gestation and lactation on reproductive performance of sows and litter performance. A total of 57 multiparous TLRI Black Pig No.1 (TBP) sows were used in this experiment. Pregnant sows were provided daily 150 ppm L-carnitine from day 91 of pregnancy to farrowing and 250 ppm/d L-carnitine provided postfarrowing throu...