BACKGROUND There is rapidly growing interest in applying measures of myocardial strain and synchrony in clinical investigations and in practice; data are limited regarding their reference ranges in healthy individuals. METHODS AND RESULTS We performed speckle-tracking-based echocardiographic measures of left ventricular myocardial strain and synchrony in healthy adults (n=739, mean age 63 yea...

BACKGROUND Because adolescents and adults act as a primary source of pertussis infection for infants, vaccination of mothers immediately postpartum is a potential strategy to reduce transmission (cocoon strategy). For this to be effective, high levels of antibodies must be achieved rapidly after vaccination. We sought to determine whether the antibody response to tetanus-diphtheria-acellular pe...

results there was a significant increase (p < 0.05) in leptin levels on day 14 (12.75 + 5.8 ng/ml) and day 21 (12.91 + 3.2 ng/ml) for age group 18-30 years compared to day 14 (11.60 + 3.2 ng/ml) and day 21 (11.60 + 3.2 ng/ml) for age group 31-40 years. leptin was positively correlated with fsh on day 14, with lh on day 7 and day 21; likewise, with progesterone on day 21 and day 28 and with estr...

This crosssectional study was conducted for a period of one year on 200 postmenopausal women attending Gynaecology outpatient department to evaluate the age at menopause and prevalence of menopausal symptoms, also to determine the awareness and attitude towards menopause and the treatment seeking behavior among these women. Eligible women were interviewed using a pretested, self-designed oral, ...

OBJECTIVE To review and evaluate the usefulness of healthy life expectancy as a global indicator of changes in a population's health. DESIGN Review of all known studies to date from the United States, mainland Europe, Canada, and the United Kingdom that have used Sullivan's method of calculating disability free life expectancy. MAIN OUTCOME MEASURES Life expectancy and disability free life ...

OBJECTIVE Menopause is a physiological life period that potentially affects various organs and systems. Therefore, a wide spectrum of signs and symptoms of eyes may be clinically observed in the postmenopausal period. AIM OF THE STUDY To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in ...

Objective. To determine the phenotypic manifestations of essential arterial hypertension (EAH) according to vitamin D receptor gene polymorphism (VDR rs10735810, rs2228570).Material and methods. The case-control study involved 100 patients with EAH stage II, 1-3 degrees blood pressure (BP), high very cardiovascular risk, 21% (21) men, 79% (79) women. mean age was 59.86 ± 6.22 y.o. control group...

Genetic and nutritional factors are determinants of total plasma homocysteine (tHCy) whose increased levels play a pathogenic role in atherothrombosis and cardiovascular disease. This study investigated the influence of sex, age, creatinine, serum folate, vitamin B12 and vitamin B6 (pyridoxal- 5-phosphate, PLP) on fasting (FtHCy) and two hour postmethionine loading levels of tHCy in 147 apparen...

BACKGROUND AND OBJECTIVES To investigate the effects of age, sex and vitamin status on total plasma homocysteine (tHCy), both after fasting (FtHCy) and two hours post-methionine load (PML-tHCy). The secondary aim was to determine the reference values for FtHCy and PML-tHCy. DESIGN AND METHODS A cohort of apparently healthy volunteers underwent blood sampling for FtHCy, PML-tHCy, creatinine, s...