7-con-O-Methylnogarol (7-OMEN), a new analog of the an thracycline antibiotic, nogalamycin, has chemotherapeutic ac tivity in several experimental mouse tumor systems. As part of the preclinical development of 7-OMEN, the cardiotoxic poten tial was evaluated in chronically dosed rabbits. Groups of 4 rabbits were dosed twice weekly i.v. with 11 or 33 mg/sq m/ week for 12 weeks, 110 sq m/mg/week ...

Abstract A store queue (SQ) is a critical component of the load execution machinery. High ILP processors require high load execution bandwidth, but providing high bandwidth SQ access is difficult. Address banking, which works well for caches, conflicts with age-ordering which is required for the SQ and multi-porting exacerbates the latency of the associative searches that load execution require...

BACKGROUND The use of wearable tools for health self-quantification (SQ) introduces new ways of thinking about one's body and about how to achieve desired health outcomes. Measurements from individuals, such as heart rate, respiratory volume, skin temperature, sleep, mood, blood pressure, food consumed, and quality of surrounding air can be acquired, quantified, and aggregated in a holistic way...

Magnetic resonance imaging (MRI)-based semi-quantitative (SQ) methods applied to knee osteoarthritis (OA) have been introduced during the last decade and have fundamentally changed our understanding of knee OA pathology since then. Several epidemiological studies and clinical trials have used MRI-based SQ methods to evaluate different outcome measures. Interest in MRI-based SQ scoring system ha...

BACKGROUND Clinicians are inaccurate at predicting survival. The 'Surprise Question' (SQ) is a screening tool that aims to identify people nearing the end of life. Potentially, its routine use could help identify patients who might benefit from palliative care services. The objective was to assess the accuracy of the SQ by time scale, clinician, and speciality. METHODS Searches were completed...

CRISTINA TRANDAFIRESCU1, FLORIN BORCAN2*, CRISTINA DEHELEAN3, ZOLTAN SZABADAI4, MIRELA NICOLOV4, CODRUTA SOICA1 1University of Medicine and Pharmacy Victor Babes, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 2 EftimieMurgu Sq., 300041, Timisoara, Romania 2University of Medicine and Pharmacy Victor Babes, Faculty of Pharmacy, Department of Analytical Chemistry, 2 EftimieMurgu Sq....

Using the Beilinson-Lusztig-MacPherson construction of the quantized enveloping algebra of gln and its associated monomial basis, we investigate q-Schur algebras Sq(n, r) as “little quantum groups”. We give a presentation for Sq(n, r) and obtain a new basis for the integral q-Schur algebra Sq(n, r), which consists of certain monomials in the original generators. Finally, when n > r, we interpre...

INTRODUCTION Subcutaneous (SQ) vaccination has emerged as standard of care in children with severe bleeding disorders to reduce unnecessary factor exposure and avoid provoking an intramuscular bleed, but little is known about comparative immunogenicity to intramuscular (IM) vaccination. AIM To confirm immunogenicity of Diphtheria Tetanus acellular Pertussis (DTaP) vaccines administered SQ to ...

PURPOSE The aim of this study was to compare the clinicopathologic prognostic factors between patients who underwent lung resection for adenocarcinoma (AD) and those with squamous cell carcinoma (SQ). METHODS A database of patients with lung AD or SQ who underwent surgery with curative intent in our department from January 2008 to December 2014 was reviewed. Associations between various clini...