Purpose: Colorectal cancers compose the third most common cancer group leading to death, with increasing rates in developed countries after lung and breast cancers. Rectal make up about 30% of all colorectal Although many factors affecting recurrence survival rectal have been identified, stage tumor is important prognostic factor. However, additional parameters that can be associated affect adj...

BACKGROUND Bro1 domains are elongated, banana-shaped domains that were first identified in the yeast ESCRT pathway protein, Bro1p. Humans express three Bro1 domain-containing proteins: ALIX, BROX, and HD-PTP, which function in association with the ESCRT pathway to help mediate intraluminal vesicle formation at multivesicular bodies, the abscission stage of cytokinesis, and/or enveloped virus bu...

In Brassica napus, floral development is a decisive factor in silique formation, and it is influenced by many cultivation practices including planting date. However, the effect of planting date on floral initiation in canola is poorly understood at present. A field experiment was conducted using a split plot design, in which three planting dates (early, 15 September, middle, 1 October, and late...

Many viruses utilize host ESCRT proteins for budding; however, influenza virus budding is thought to be ESCRT-independent. In this study we have found a role for the influenza virus M2 proton-selective ion channel protein in mediating virus budding. We observed that a highly conserved amphipathic helix located within the M2 cytoplasmic tail mediates a cholesterol-dependent alteration in membran...

BACKGROUND AND OBJECTIVES Epithelial to mesenchymal transition (EMT) is considered to play an important role in cancer invasion. Tumor budding is a prognostic factor in esophageal squamous cell carcinoma (ESCC). The aim of this study was to explore the correlation between EMT and tumor budding. METHODS Surgical specimens from 78 cases of ESCC resected without preoperative treatment between 20...

As a result of global climate change and urban development, the interaction between form carbon emissions has become frontier issue key area emission research. This paper presents scientometric analysis 2439 academic publications 2002 2021 on to explore current state research future development potential. Citespace VOSviewer were primary tools. The results showed following: (1) number articles ...

This topic with the examples of budding bear series guided by sustainable design, in three dimensional animation role comprehensive analysis comparison, induction and summary, hope through design to promote application development, under artistic expression innovation concept, for study provide theoretical basis. article first 3 d animation, example, role, introduce bud content, were discussed ...