For differential diagnosis between hypercalcemia-induced bone metastasis and humoral hypercalcemia of malignancy (HHM), serum parathyroid hormone-related protein (PTHrP) concentrations were measured in normal subjects and patients with malignancy-associated hypercalcemia according to the presence or absence of bone metastasis, using a new sensitive PTHrP(109-141) radioimmunoassay system. The se...

http://www.sciencemag.org/cgi/content/full/291/5501/109 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/291/5501/109/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://w...

A 3-year-old female toddler was referred to our pediatric emergency unit with a 2-week history of fatigue, anorexia, progressive pallor, and vomiting. Medical history showed that iron deficiency anemia was diagnosed one year before and oral iron-sulfate was given. She also had a one year history of intermittent vomiting. Her diet seemed adequate in iron-rich foods. Chest X-ray and abdominal ult...

Proteolytic processing of the respiratory syncytial virus F (fusion) protein results in the generation of the disulfide-linked subunits F1 and F2 and in the release of pep27, a glycopeptide originally located between the two furin cleavage sites FCS-1 (RKRR(136)) and FCS-2 (RAR/KR(109)). We made use of reverse genetics to study the importance of FCS-2 and of pep27 for BRSV replication in cell c...

DOUGLAS SHEIL*, AGUS SALIM*†, JÉRÔME CHAVE‡, JEROME VANCLAY§ and WILLIAM D. HAWTHORNE¶ * Center for International Forestry Research, PO Box 6596 JKPWB, Jakarta 10065, Indonesia, † National Centre for Epidemiology and Population Health, Australian National University, Mills Road, Acton ACT 0200, Australia, ‡ Laboratoire Evolution et Diversité Biologique, UMR CNRS 5174, 118, route de Narbone, F-3...

OBJECTIVE To determine patient factors and fracture morphology of dogs presented with mandibular fractures to a small animal referral centre in South Africa. METHODS Patient data on age, sex, breed and aetiology of dogs with mandibular fractures were recorded. The fractures were classified according to the anatomical location, displacement, fracture type, fracture line direction, periodontal ...

1. Competition for light is a central issue in ecological questions concerning forest tree differentiation and diversity. Here, using 213,106 individual stem records derived from a national survey in Ghana, West Africa, we examine the relationship between relative crown exposure, ontogeny and phylogeny for 109 canopy species. 2 2. We use a generalized linear model (GLM) framework to allow inter...