CONDITIONAL DISCRIMINATIVE FUNCTIONS OF MEANINGFUL STIMULI AND ENHANCED EQUIVALENCE CLASS FORMATION by Roxana I. Nedelcu Adviser: Dr. Lanny Fields, Ph.D. Two experiments explored how the formation of two 3-node, 5member equivalence classes by college students was influenced by the prior acquisition of conditional discriminative functions by one of the abstract stimuli, designated as C, in the c...

Proinflammatory cytokines have been shown to influence the expression and function of the glucocorticoid receptor (GR). Specifically, several studies have found that cytokines induce a decrease in GR function, as evidenced by reduced sensitivity to glucocorticoid effects on functional end points. To investigate the potential mechanism(s) involved, we examined the impact of the proinflammatory c...

Vascularization is an important factor that affects diabetic wound healing. There is increasing evidence that myeloid cell lineages play a role in neovascularization. In this study, the efficiency of Gr-1+CD11b+ myeloid cells to home to the site of injury and enhance diabetic wound healing by neoangiogenesis after intravenous administration was investigated. Gr-1+CD11b+ myeloid cells were injec...

the interaction between nitrogen levels: 100, 150 and 175 kg ha-1, as ammonium sulfate (ams) and glyphosate: 1) 61.5 gr a.i. ha-1 sprayed in three parts, 30, 40 and 50 dap, 2) 61.5 gr a.i. ha-1 sprayed in two parts, 30 and 50 dap, 3) 86 gr a.i. ha-1 sprayed in three parts as level one, 4) 86 gr a.i. ha-1 sprayed in two parts as level two on broomrape shoot density and dry mater and tomato yield...

Despite new treatments for castrate-resistant prostate cancer (CRPC), the prognosis of patients with CRPC remains bleak due to acquired resistance to androgen receptor (AR)-directed therapy. The glucocorticoid receptor (GR) and AR share several transcriptional targets, including the anti-apoptotic genes serum and glucocorticoid-regulated kinase 1 (SGK1) and Map kinase phosphatase 1 (MKP1)/dual ...

The putative eukaryotic translation initiation factor 5A (eIF5A) is a highly conserved and essential protein present in all organisms except bacteria. To be activated, eIF5A requires the conversion of a specific residue of lysine into hypusine. This hypusine modification occurs posttranslationally in two enzymatic steps, and the polyamine spermidine is the substrate. Despite having an essential...

BACKGROUND AND PURPOSE We performed a retrospective analysis of the prognostic factors in patients treated with local intra-arterial thrombolysis (LIT). The purpose of this study was to evaluate the safety and efficacy of LIT using urokinase in patients with acute ischemic stroke of the anterior or posterior circulation and to determine the influence of clinical and radiological parameters on o...

BACKGROUND Dietary quercetin improves cardiovascular health, relaxes some vascular smooth muscle and has been demonstrated to serve as a substrate for the cyclooxygenase enzyme. AIMS 1. To test quantitatively a potential direct vasodilatory effect on intramural coronary resistance artery segments, in different concentrations. 2. To scale vasorelaxation at different intraluminal pressure loads...