نتایج جستجو برای: 1 sfrp

تعداد نتایج: 2752679  

2014
Jongbum Kim Sangsoo Kim

Aberrant DNA methylation, as an epigenetic marker of cancer, influences tumor development and progression. We downloaded publicly available DNA methylation and gene expression datasets of matched cancer and normal pairs from the Cancer Genome Atlas Data Portal and performed a systematic computational analysis. This study has three aims to screen genes that show hypermethylation and downregulate...

2006
Irina Leaf Jason Tennessen Mahua Mukhopadhyay Heiner Westphal William Shawlot

Secreted frizzled related protein (Sfrp) genes encode extracellular factors that can modulate Wnt signaling. During early post-implantation mouse development Sfrp5 is expressed in the anterior visceral endoderm (AVE) and the ventral foregut endoderm. The AVE is important in anterior–posterior axis formation and the ventral foregut endoderm contributes to multiple gut tissues. Here to determine ...

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