OBJECTIVE To assess the effect of the inhibition of the angiotensin-converting enzyme on the collagen matrix (CM) of the heart of newborn spontaneously hypertensive rats (SHR) during embryonic development. METHODS The study comprised the 2 following groups of SHR (n=5 each): treated group - rats conceived from SHR females treated with enalapril maleate (15 mg. kg-1.day-1) during gestation; an...

OBJECTIVE To describe the distribution of elastic fibres in the developing male urethra and to provide stereological data of the concentration of elastic fibres in the human urethra. MATERIALS AND METHODS Urethras were obtained from 10 fresh normal human fetuses at 15-36 weeks of gestation. A place-matched spongy urethra of a 27-year-old normal adult man was also analysed. Samples were fixed ...

Appropriation of signalling pathways facilitates poxvirus replication. Poxviruses, as do most viruses, try to modify the host cell environment to achieve favourable replication conditions. In the present study, we show that the early growth response 1 gene (egr-1) is one of the host cell factors intensely modulated by the orthopoxviruses VV (vaccinia virus) and CPV (cowpox virus). These viruses...

Background: Amiodarone is a drug that is used for treatment of cardiac arrhythmia after cardiac ischemia. This drug as b blocker decreases arrhythmia rate but it has many side effects on different tissues. Since there are rare reports about changes of lacrimal glands, this research has been carried out to study the morphological and ultrastructural changes of lacrimal gland cells after amiodaro...

Vaccinia virus (VV) and other orthopoxviruses express a soluble type I interferon (IFN) receptor that for VV strain Western Reserve is encoded by gene B18R. The 60-65 kDa glycoprotein is related to the interleukin-1 receptors and is a member of the immunoglobulin superfamily, unlike other type I IFN receptors, which belong to the class II cytokine receptor family. The receptor has high affinity...

Many polygon mesh algorithms operate in a local manner, yet are formally specified using global indexing schemes. We address this discrepancy by defining a set of local operations on polygon meshes in relational, index-free terms. We also introduce the vv programming language to express these operations in a machine-readable form. We then apply vv to specify several surface subdivision algorith...

Correspondence To the Editor: I reviewed the article Quantification of adventitial vasa vasorum (VV) vascularization in double‑injury restenotic arteries by Meng et al. with great interest, which described their experiment about adventitial VV and postangioplasty restenosis. Percutaneous transluminal angioplasty is now widely used for the treatment of atherosclerotic lesions in various arteries...

Drought is a major natural hazard that impacts agriculture, the environment, and socio-economic conditions. In 2018 2019, Europe experienced severe drought due to below average precipitation high temperatures. stress affects moisture content structure of agricultural crops can result in lower yields. Synthetic Aperture Radar (SAR) observations are sensitive dielectric geometric characteristics ...