Corresponding author Antonella Tammaro Dermatology Unit, NESMOS Department, S. Andrea Hospital, University of Rome “Sapienza” Via di Grottarossa, 1035 00189 Rome (RM), Italy Phone: +39 06 3377 5907 Fax: +39 06 3377 5378 E-mail: [email protected]

121 words Word count: 3105 words Review Article Arthritis Care & Research DOI 10.1002/acr.20228 © 2010 American College of Rheumatology Received: Mar 06, 2010; Revised: Apr 06, 2010; Accepted: Apr 09, 2010

Astronomische NachrichtenVolume 344, Issue 6 e239006 ISSUE INFORMATIONFree Access Information: Astron. Nachr. 06/2023 First published: 24 August 2023 https://doi.org/10.1002/asna.20239006AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms and Conditions of Use check box below share version ar...

The presence of the DNA repair protein, 06-alkylguanine-DNA alkyltransferase (AGT) in tumor cells is a significant source of resistance to chemotherapeutic alkylnitrosoureas and alkyltriazenes. 06-Benzylguanine provides a means to effectively inactivate the AGT protein and increase the chemotherapeutic effectiveness of chloroethylating and methylating agents in vitro and in human tumor xenograf...