High adiposity is deleteriously associated with brain health, and may disproportionately affect white matter integrity; however, limited information exists regarding the mechanisms underlying the association between body mass (BMI) and white matter integrity. The present study evaluated whether vascular and inflammatory markers influence the relationship between BMI and white matter in healthy ...

An important class of concurrent objects are those that are non-blocking, that is, whose operations are not contained within mutually exclusive critical sections. A non-blocking object can be accessed by many threads at a time, yet update protocols based on atomic Compare-And-Swap operations can be used to guarantee the object's consistency. In this paper we take a practical look at the Compare...

Iron deficiency is one of the most widespread nutritional disorders in both developing and industrialized countries, making it a global public health concern. Anemia, mainly due to iron deficiency, affects one third of the world’s population and is concentrated in women and children below 5 years of age. Iron deficiency anemia has a profound impact on human health and productivity, and the effe...

Parity encoded redundant disk arrays provide highly reliable, cost effective secondary storage with high performance for reads and large writes. Their performance on small writes, however, is much worse than mirrored disks — the traditional, highly reliable, but expensive organization for secondary storage. Unfortunately, small writes are a substantial portion of the I/O workload of many import...

Recovery of kidney function following an episode of acute kidney injury (AKI) is now acknowledged as a vital patientcentered outcome with clear health economic implications. In approximately 5–8% of critically ill patients with more severe forms of AKI, support with renal replacement therapy (RRT) is provided. Recent data have suggested that rates of RRT utilization in AKI are increasing. Despi...

A micro kernel-based operating system architecture is becoming common for advanced distributed computing systems. Advantages of using such micro kernel for real-time applications is that the preemptability of the kernel is better, the size of the kernel becomes much smaller, and addition of new service is easier. However, such a micro kernel alone cannot provide a predictable, distributed real-...

In this paper we describe restartable atomic sequences, an optimistic mechanism for implementing simple atomic operations (such as Test-And-Set) on a uniprocessor. A thread that is suspended within a restartable atomic sequence is resumed by the operating system at the beginning of the sequence, rather than at the point of suspension. This guarantees that the thread eventually executes the sequ...

Myelodysplastic syndrome (MDS) is a complication of conventional antineoplastic therapy but has rarely been reported after autologous bone marrow transplantation (ABMT). We reviewed records of 206 patients who underwent ABMT for lymphoma at the University of Minnesota (Minneapolis, MN) between 1974 and 1993. Of 206 patients who underwent ABMT for non-Hodgkin's lymphoma (NHL) or Hodgkin's diseas...

BACKGROUND Men with high-risk prostate cancer are often thought to have very poor outcomes in terms of disease control and survival even after definitive treatment. However, results after external beam radiotherapy have improved significantly through dose escalation and the use of androgen deprivation therapy (ADT). This report describes long-term findings after low-dose (< 75.6 Gy) or high-dos...