We measured free thyroxin (FT4) in dried blood samples from 10 000 euthyroid and 29 hypothyroid newborns (three with transient hypothyroidism and 26 permanent). In euthyroids, the mean FT4 concentration was 16.9 (SD 4.5) pmol/L. Preterm babies had low concentrations of FT4, and values were closely related to birth weight when less than 2500 g. Assay of blood-spot FT4 appears to be specific as a...

OBJECTIVE To evaluate the cost-effectiveness of the European community-based project '10 000 Steps Ghent', an intervention that resulted in a significant decrease in sedentary time and a significant increase in step counts (896 steps/d) and self-reported walking (66 min/week). DESIGN An age- and gender-dependent Markov model, with a time horizon of 20 years and a cycle length of 1 year, estim...

Image classification is a critical task for both humans and computers. One of the challenges lies in the large scale of the semantic space. In particular, humans can recognize tens of thousands of object classes and scenes. No computer vision algorithm today has been tested at this scale. This paper presents a study of large scale categorization including a series of challenging experiments on ...

This special issue of Cognitive Systems Research presents a collection of remarkable papers on cognitive modeling based on communications delivered at ICCM-2006, the Seventh International Conference on Cognitive Modeling (Fum, Del Missier, & Stocco, 2006) held in Trieste, Italy, from April 5th to 8th, 2006. Being the organizers and chairmen of the conference, we have been invited to serve as gu...

UNLABELLED This study examined the determinants of attaining/not attaining 10 000 steps per day among older women. METHODS Daily step counts over 7 days were measured using accelerometry. Self-reported environmental characteristics, self-efficacy, social support and functional limitations were assessed in 128 older women. The presence of areas for activity within 1 km of each participant's re...

Using a computer database, the author investigated the histopathology of 10 000 consecutive gastric specimens collected in the last 12 years 2002-2013 at his pathology laboratory in a relatively large hospital in Japan. Examination of histological sections was done when appropriate. The gastric specimens were made up of 8579 benign conditions and 1421 malignant lesions. The latter comprised gas...

BACKGROUND Recent studies have demonstrated an association between moderate kidney dysfunction and sudden cardiac death in people with cardiovascular disease. METHODS AND RESULTS The study was a longitudinal analysis among 4465 participants from the Cardiovascular Health Study without prevalent cardiovascular disease at baseline. Cystatin C and creatinine were measured from baseline sera. Sud...