Rheumatoid arthritis is the most common systematic autoimmune disease and its etiology is believed to have both strong genetic and environmental components. We demonstrate the utility of including genetic and clinical phenotypes as covariates within a linkage analysis framework to search for rheumatoid arthritis susceptibility loci. The raw genotypes of 1302 affected relative pairs were combine...

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In the Essential Health Benefits, Actuarial Value, and Accreditation final rule, published in the Federal Register, HHS requires use of an AV Calculator by non-grandfathered health insurance plans offered in the individual and small group markets, both inside and outside of the Affordable Insurance Exchanges (Exchanges) for the purposes of determining levels of coverage. Section 1302(d)(2)(A) o...

Correspondence: Roger R Dmochowski Department of Urologic Surgery, vanderbilt University Medical Center, A-1302, Medical Center North, Nashville, TN 37232, USA Tel +1 615 343 5602 Fax +1 615 322 8990 email [email protected] Abstract: Overactive bladder (OAB) is a common condition that causes a profound impact on an individual’s overall health and quality of life. Muscarinic recept...

In this paper, a new S-type eigenvalue localization set for a tensor is derived by dividing [Formula: see text] into disjoint subsets S and its complement. It is proved that this new set is sharper than those presented by Qi (J. Symb. Comput. 40:1302-1324, 2005), Li et al. (Numer. Linear Algebra Appl. 21:39-50, 2014) and Li et al. (Linear Algebra Appl. 481:36-53, 2015). As applications of the r...

Lipopolysaccharide is a virulent cell membrane component of Gram negative bacteria. It is also a potent activator of immune system capable of triggering cytokine release from cells of different origin. Life threatening diseases as septic shock following infection with Gram negative bacteria is mediated mainly by LPS (Kawaiand Akira, 2010). Lipopolysaccharide (LPS), is a complex structure and is...

during an eight month prospective study, 8240 newborns were examined for detection of congenital dislocation of the hip from oct. 23, 1991 to june 22, 1992. on first examination we found 1302 neonates (158/1000 live births) to have abnormal hips 1063 (81.6%) were prone to subluxation (subluxatable), 218 (16.81 %) prone to dislocation (dislocatable), 17 (1.3%) were dislocated and 4 (0.3%) were t...