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mit Actinomycin und RNAse behandelt waren) in Sucroselösung suspendiert und in einem PotterElvehjem-Homogenisator zerbrochen. Die Zellwandund Kernfraktion wurde durch Zentrifugation von den übrigen Bestandteilen (Überstand) getrennt9 und die Aktivitätsverteilung gemessen. Ungefähr 50% der Aktivität im Überstand weisen auf das Eindringen der externen Polymeren in das Zellplasma hin. Die am Niede...
The paper studies the compressibility of directly compressible tableting materials with dry binders, spray-dried lactose and microcrystalline cellulose, and glyceryl dibehenate at various concentrations. Compressibility was evaluated by means of the energy profile of compression and tensile strength of tablets. Release rate of the active ingredient, salicylic acid, from the tablets was also exa...
Apparent motion is an illusory perception of movement that can be induced by alternating presentations of static objects. Already in Wertheimer's early investigation of the phenomenon [Wertheimer, M. (1912). Experimentelle Studien über das Sehen von Bewegung. Zeitschrift fur Psychologie, 61, 161-265], he mentions that voluntary attention can influence the way in which an ambiguous apparent moti...
A new, optimized, antimicrobial enzyme system was developed for the control of wound bioburden. This Glucose oxidase-Lactoperoxidase-Guaiacol (GLG) system was analyzed for antimicrobial activity and cytotoxicity. The susceptibility of a wide range of antibiotic-resistant bacterial strains to the GLG-enzyme system was analyzed using minimum inhibitory concentration (MIC90), minimum bactericid...
BACKGROUND Ambient air pollution has been associated with increased cardiovascular morbidity and mortality. In Reykjavik, Iceland, air pollutant concentrations exceed official health limits several times every year. The aim was to study the association of concentrations of NO2, O3, PM10, and H2S in the Reykjavik capital area with the dispensing of anti-angina pectoris medication, glyceryl trini...
un système dynamique (X, F, m, T) une distance Dm sur l’ensemble des histoires, en terme de l’entropie de von Neumann-Shannon ; 3) qu’on peut définir un ensemble à un paramètre de distances ultramétriques D(03B1)m en utilisant les mesures d’information de degré a, a ~ [0, 1]; 4) que le paramètre Y utilisé dans la théorie des systèmes désordonnés est une fonction de la mesure d’information de de...
In a double-blind clinical trial the antianginal effects of nifedipine (30 and 60 mg/day) and propranolol 240 and 480 mg/day) and a combination of both drugs were compared with those of placebo in 16 patients with severe exertional angina pectoris. Response to treatment was assessed by the objective criteria of 16-point precordial exercise mapping and 48-hour ambulatory electrocardiographic mon...
Americo Abbruzzese Herbert L. Abrams Stanley J. Adelstein Milton H. Alper William A. Altemeir Alan G. Birtch Bruce R. Brener John R. Brooks Hathorn P. Brown Theodore Colton Oliver Cope Nathan P. Couch Chilton Crane Gustave J. Dammin Donald P. Dressler J. Englebert Dunphy Richard W. Dwight Robert M. Filler William P. Grigsby Richard E. Hicks David Littmann Emmanuel Mannarino William V. McDermott...
Hydrotropic polymer micelle system has been developed for delivery of poorly water-soluble drugs such as paclitaxel. Hydrotropic polymers based on N,N-diethylnicotinamide were synthesized and used as a hydrophobic block for constructing amphiphilic block copolymers. The hydrotropic block copolymers self-assembled to form micelles in aqueous media. The size of the prepared polymer micelles was i...
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